SPRY3 Antibody

說明書

產品詳情

Uniprot No.：

O43610
基因名：

SPRY3
別名：

SPRY3 antibody; Protein sprouty homolog 3 antibody; Spry-3 antibody
宿主：

Rabbit
反應種屬：

Human,Mouse,Rat
免疫原：

Human SPRY3
免疫原種屬：

Homo sapiens (Human)
抗體亞型：

IgG
純化方式：

Antigen Affinity purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
產品提供形式：

Liquid
應用范圍：

ELISA,WB
Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Inhibits neurite branching, arbor length and neurite complexity. Inhibits EGF-mediated p42/44 ERK signaling. Negatively regulates the MAPK cascade, resulting in a reduction of extracellular matrix protein accumulation. May function as an antagonist of fibroblast growth factor (FGF) pathways and may negatively modulate respiratory organogenesis.
基因功能參考文獻：
1. SPRY3 is a candidate susceptibility locus for autism and related or over-lapping disorders such as ataxia. PMID: 26089202
2. Spry 1, 2 and 3 expression was observed in placental tissue from all three trimesters PMID: 15950061
3. the Sprouty/Caveolin-1 interaction modulates signaling in a growth factor- and Sprouty isoform-specific manner PMID: 16877379
亞細胞定位：

Cytoplasm.
蛋白家族：

Sprouty family
組織特異性：

Widely expressed; particularly in the fetal tissues. Expressed in the brain with expression the highest in Purkinje cells in the cerebellum (at protein level). Expressed in the myocardium of the heart.
數據庫鏈接：

HGNC: 11271

OMIM: 300531

KEGG: hsa:10251

STRING: 9606.ENSP00000302978

UniGene: Hs.381912

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