SPG21 Antibody, HRP conjugated
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中文名稱：SPG21兔多克隆抗體, HRP偶聯
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貨號：CSB-PA889158LB01HU
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規格：￥880
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其他：
產品詳情
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產品名稱：Rabbit anti-Homo sapiens (Human) SPG21 Polyclonal antibody
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Uniprot No.：
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基因名：
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別名：SPG21 antibody; ACP33 antibody; BM-019 antibody; GL010 antibody; Maspardin antibody; Acid cluster protein 33 antibody; Spastic paraplegia 21 autosomal recessive Mast syndrome protein antibody; Spastic paraplegia 21 protein antibody
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宿主：Rabbit
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反應種屬：Human
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免疫原：Recombinant Human Maspardin protein (1-308AA)
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免疫原種屬：Homo sapiens (Human)
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標記方式：HRP
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：>95%, Protein G purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 -
產品提供形式：Liquid
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應用范圍：ELISA
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Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：May play a role as a negative regulatory factor in CD4-dependent T-cell activation.
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基因功能參考文獻：
- HBV X gene enhanced SPG21 gene promoter activity, SPG21 mRNA expression and SPG21 protein production in HepG2 cells in a dose-dependent manner. PMID: 21205478
- frameshift results in the premature termination of the encoded product, which is designated "maspardin" (Mast syndrome, spastic paraplegia, autosomal recessive with dementia) PMID: 14564668
- Data report that maspardin localizes prominently to cytoplasm as well as to membranes, possibly at trans-Golgi network/late endosomal compartments, and that maspardin interacts with the aldehyde dehydrogenase ALDH16A1. PMID: 19184135
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相關疾病：Spastic paraplegia 21, autosomal recessive (SPG21)
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亞細胞定位：Cytoplasm, cytosol. Membrane; Peripheral membrane protein. Endosome membrane; Peripheral membrane protein. Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein. Note=Partially localized in the cytosol but also accumulated on an intracellular vesicular compartment. Colocalizes with CD4 on endosomal/trans-Golgi network.
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蛋白家族：AB hydrolase superfamily
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組織特異性：Expressed in all tissues tested, including heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Expressed in J.CaM1.6, HuT 78 and HeLa cell lines (at protein level).
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數據庫鏈接：
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