SOX8 Antibody
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中文名稱：SOX8兔多克隆抗體
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貨號：CSB-PA022436GA01HU
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規格：￥3,900
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其他：
產品詳情
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Uniprot No.：
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基因名：SOX8
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別名：MGC24837 antibody; SOX 8 antibody; Sox8 antibody; SOX8_HUMAN antibody; SRY (sex determining region Y) box 8 antibody; SRY box 8 antibody; SRY box containing gene 8 antibody; Transcription factor SOX 8 antibody; Transcription factor SOX-8 antibody; Transcription factor SOX8 antibody
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宿主：Rabbit
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反應種屬：Human
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免疫原：Human SOX8
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免疫原種屬：Homo sapiens (Human)
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抗體亞型：IgG
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純化方式：Antigen Affinity purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
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產品提供形式：Liquid
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應用范圍：ELISA,WB
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Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Transcription factor that may play a role in central nervous system, limb and facial development. May be involved in male sex determination. Binds the consensus motif 5'-[AT][AT]CAA[AT]G-3'.
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基因功能參考文獻：
- SOX8 bounds to the promoter region of FZD7 and induces the FZD7-mediated activation of the Wnt/beta-catenin pathway and confers chemoresistance and stemness properties and mediates epithelial mesenchymal transition in chemoresistant tongue squamous cell carcinoma. PMID: 29071717
- Suggest that miRNA-124 may regulate non-small cell lung carcinoma cell proliferation via decreasing SOX8. PMID: 25400731
- SOX8 mRNA levels decrease during in vitro dedifferentiation of human articular chondrocytes and increase during chondrogenic differentiation of mesenchymal stromal cells. PMID: 24449344
- SOX8 promotes cancer cell proliferation and its expression is correlated with elevated beta-catenin levels in hepatocellular carcinoma PMID: 24643625
- The SOX8 single nucleotide polymorphism, rs2744148, is associated with increased genetic risk for multiple sclerosis. PMID: 23739915
- Quantitative changes of enteric glia represented by SOX8 provide a basis for pathological assessment of glial proliferation and/or degeneration in the diseased gut. PMID: 18512230
- SOX2 and SOX17 expression patterns can distinguish between seminoma and embryonal carcinoma, and this distinction may be diagnostically useful. PMID: 19369635
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亞細胞定位：Nucleus.
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數據庫鏈接：
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