SLC7A2 Antibody, Biotin conjugated
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中文名稱：SLC7A2兔多克隆抗體, Biotin偶聯
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貨號：CSB-PA021714LD01HU
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規格：￥880
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其他：
產品詳情
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產品名稱：Rabbit anti-Homo sapiens (Human) SLC7A2 Polyclonal antibody
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Uniprot No.：
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基因名：SLC7A2
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別名：ATRC2 antibody; 20.5 antibody; Amino acid transporter; cationic 2 (low affinity) antibody; ATRC 2 antibody; CAT 2 antibody; CAT-2 antibody; CAT2 antibody; Cat2a antibody; Cat2b antibody; Cationic amino acid transporter 2A antibody; cationic amino acid transporter; y+ system; low affinity cationic amino acid transporter 2 antibody; CTR2_HUMAN antibody; HCAT 2 antibody; HCAT2 antibody; Low affinity cationic amino acid transporter 2 antibody; OTTHUMP00000216432 antibody; OTTHUMP00000216433 antibody; OTTMUSP00000041667 antibody; OTTMUSP00000041669 antibody; RCAT2 antibody; SLC7A 2 antibody; Slc7a2 antibody; Solute carrier family 7 member 2 antibody; T cell early activation protein antibody; Tea antibody
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宿主：Rabbit
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反應種屬：Human
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免疫原：Recombinant Human Cationic amino acid transporter 2 protein (604-658AA)
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免疫原種屬：Homo sapiens (Human)
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標記方式：Biotin
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：>95%, Protein G purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 -
產品提供形式：Liquid
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應用范圍：ELISA
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Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Functions as permease involved in the transport of the cationic amino acids (arginine, lysine and ornithine); the affinity for its substrates differs between isoforms created by alternative splicing. Isoform 1 functions as permease that mediates the transport of the cationic amino acids (arginine, lysine and ornithine), and it has much higher affinity for arginine than isoform 2. Isoform 2 functions as low-affinity, high capacity permease involved in the transport of the cationic amino acids (arginine, lysine and ornithine). May play a role in classical or alternative activation of macrophages via its role in arginine transport.
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基因功能參考文獻：
- genetic association studies in population in Tennessee: Data suggest that an SNP in SLC7A2 (rs2720574) is associated with response to dietary calcium and magnesium in prevention of colorectal polyps and colorectal ademonas. PMID: 28501704
- Identification of cysteine residues in human cationic amino acid transporter hCAT-2A that are targets for inhibition by N-ethylmaleimide. PMID: 24019517
- A chimera carrying the functional domain of the orphan protein SLC7A14 in the backbone of SLC7A2 mediates trans-stimulated arginine transport. PMID: 22787143
- Addition of spermine or knockdown of CAT2 inhibited L-Arg uptake, NO production, and iNOS protein levels, whereas knockdown of ODC had the opposite effect. CAT2 and ODC were increased in mouse and human H pylori gastritis tissues. PMID: 20600019
- Insulin increased L-arginine transport and the mRNA levels for hCAT-1 and hCAT-2B PMID: 15064952
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亞細胞定位：Cell membrane; Multi-pass membrane protein.
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蛋白家族：Amino acid-polyamine-organocation (APC) superfamily, Cationic amino acid transporter (CAT) (TC 2.A.3.3) family
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組織特異性：Expressed at high levels in the skeletal muscle, placenta and ovary. Expressed at intermediate levels in the liver and pancreas and at low levels in the kidney and heart.
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數據庫鏈接：
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