SLC30A1 Antibody
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中文名稱：SLC30A1兔多克隆抗體
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貨號：CSB-PA060118
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規格：￥1090
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其他：
產品詳情
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Uniprot No.：
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基因名：
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別名：SLC30 A1 antibody; SLC30A 1 antibody; SLC30A1 antibody; Solute carrier family 30 (zinc transporter), member 1 antibody; Solute carrier family 30 (zinc transporter), member1 antibody; Solute carrier family 30 member 1 antibody; Solute carrier family 30, member 1 antibody; Zinc transporter 1 antibody; Zinc transporter1 antibody; ZNT 1 antibody; ZnT-1 antibody; ZNT1_HUMAN antibody; ZRC 1 antibody; ZRC1 antibody
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宿主：Rabbit
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反應種屬：Human
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免疫原：Synthesized peptide derived from the Internal region of Human ZnT-1.
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
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抗體亞型：IgG
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純化方式：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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產品提供形式：Liquid
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應用范圍：WB, IHC, ELISA
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推薦稀釋比：
Application Recommended Dilution WB 1:500-1:2000 IHC 1:100-1:300 ELISA 1:5000 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
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靶點詳情
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功能：May be involved in zinc transport out of the cell.
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基因功能參考文獻：
- This study showed that there was a significant increase in protein levels of ZnT1 in the prefrontal cortex in Major depressive disorder, relative to control subjects PMID: 27661418
- MTF1 heads a hierarchy of zinc sensors, and through controlling the expression of a raft of metallothioneins and other key proteins involved in controlling intracellular zinc levels (e.g. ZnT1) alters zinc buffering capacity and total cellular zinc content. PMID: 26824222
- Data indicate that zinc transporters ZnT1 and Zip1 were the most abundantly expressed zinc transporters in leukocytes. PMID: 24488210
- ZnT-1 extrudes zinc from mammalian cells by functioning as a Zn(2+)/H(+) exchanger. PMID: 24951051
- Data indicate that the expression levels of ZnT and ZIP families in the three cell lines, when treated with high concentration of ZnSO4, increased and decreased corresponding to their functions, respectively. PMID: 23839533
- ZnT-1 augments CaV3.1 and CaV3.2 channel signals by stimulating the Ras-ERK pathways. PMID: 22572848
- The results of this study showed that signi fi cant positive correlations between ZIP1,ZnT1, and ZnT6 in most brain in patient with Alzheimer's disease. PMID: 22349685
- The metallothionein gene had a higher expression in the blood, when compared to zinc transporters ZnT-1, Zip-1, and Zip-3 (p=0.01 in obese patients. PMID: 21053094
- Differentiated Caco-2 cells tolerate significantly higher levels of zinc compared to undifferentiated Caco-2 cells, which was accompanied by upregulated ZnT-1 and downregulated ZIP1 levels. PMID: 21103883
- the transporter ZnT1 at the basolateral membrane, regulate the amount of zinc released to the portal circulation for systemic distribution PMID: 21462106
- GSPE and EGCG inhibit the expression of zinc-binding metallothioneins and plasma membrane zinc exporter ZnT1 (SLC30A1). PMID: 20471814
- our results suggest that alterations in Zn transport proteins ZnT-1, ZnT-4 and ZnT-6 may contribute to the pathology observed in preclinical Alzheimer's disease subjects before onset of clinical symptoms PMID: 19371353
- The effects of zinc and cadmium on the expression and membrane localization of metallothioneins and ZNT1 in hepatoma cells are reproted. PMID: 19900532
- ZnT-1 expression was found to be augmented in the atria of atrial tachycardia patients. PMID: 20201890
- AIDL cells exhibited a lower expression of zinc transporter 1 (ZnT1) and higher expression of ZnT3 than LNCaP cells. PMID: 14662799
- Our findings therefore indicate that ZnT-1 modulates the permeation of cations through LTCC, thereby, regulating cation homeostasis through this pathway. PMID: 15451416
- correlation analysis of ZnT-1 levels and senile plaque and neurofibrillary tangle counts of Alzheimer's disease showed a significant positive correlation PMID: 16179263
- regulation of ZnT-1 protein in human breast cancer xenografts PMID: 17786585
- This study provides evidence for increased ZnT-1 expression in atria of patients with atrial fibrillation. PMID: 17971132
- hZnT-1 is the most regulated zinc exporter in leukocytes. it i sfound in the plasma membrane. PMID: 17971500
- HPV16 E5 protein binds to EVER and ZnT-1 and blocks their negative regulation PMID: 18158319
- Data show that ZNT1 is extensively present in the Abeta-positive plaques in the cortex of human AD brains. PMID: 18639746
- zinc transporter 1 is an endogenous inhibitor of L-type calcium channels PMID: 19767393
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亞細胞定位：Cell membrane; Multi-pass membrane protein.
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蛋白家族：Cation diffusion facilitator (CDF) transporter (TC 2.A.4) family, SLC30A subfamily
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