SLC27A1 Antibody
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中文名稱：SLC27A1兔多克隆抗體
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貨號：CSB-PA232605
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規格：￥1100
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圖片：
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The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA232605(SLC27A1 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ×200) -
The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using CSB-PA232605(SLC27A1 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ×200)
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其他：
產品詳情
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Uniprot No.：
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基因名：
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別名：SLC27A1 antibody; ACSVL5 antibody; FATP1Long-chain fatty acid transport protein 1 antibody; FATP-1 antibody; Fatty acid transport protein 1 antibody; EC 6.2.1.- antibody; Solute carrier family 27 member 1 antibody
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宿主：Rabbit
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反應種屬：Human
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免疫原：Synthetic peptide of Human SLC27A1
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
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抗體亞型：IgG
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純化方式：Antigen affinity purification
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
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產品提供形式：Liquid
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應用范圍：ELISA,IHC
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推薦稀釋比：
Application Recommended Dilution ELISA 1:2000-1:5000 IHC 1:50-1:200 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Mediates the ATP-dependent import of long-chain fatty acids (LCFA) into the cell by mediating their translocation at the plasma membrane. Has also an acyl-CoA ligase activity for long-chain and very-long-chain fatty acids. May act directly as a bona fide transporter, or alternatively, in a cytoplasmic or membrane-associated multimeric protein complex to trap and draw fatty acids towards accumulation. Plays a pivotal role in regulating available LCFA substrates from exogenous sources in tissues undergoing high levels of beta-oxidation or triglyceride synthesis. May be involved in regulation of cholesterol metabolism. Probably involved in fatty acid transport across the blood barrier.
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基因功能參考文獻：
- Neonatal phthalate ester exposure induced placental MTs, FATP1 and HFABP mRNA expression PMID: 26867681
- Several proteins that are expressed in the epidermis have been proposed to facilitate the uptake of long-chain fatty acids (LCFA) in mammalian cells, CD36, fatty acid binding protein, and FATP. [review] PMID: 24120574
- Observational study of gene-disease association. (HuGE Navigator) PMID: 20965718
- Observational study of gene-disease association. (HuGE Navigator) PMID: 19913121
- Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator) PMID: 20628086
- FATP1 inhibits 11-cis retinol formation via interaction with the visual cycle retinoid isomerase RPE65 and lecithin:retinol acyltransferase PMID: 20356843
- Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator) PMID: 20416077
- exogenously supplied fatty acids are preferentially channeled by an FATP1-linked mechanism into the TG biosynthetic pathway; such internalized lipids downregulate de novo sphingomyelin and cholesterol metabolism in growing 293 cells PMID: 12235169
- FATP1 might play a role in post-prandial lipid metabolism and development of cardiovascular disease. PMID: 12818409
- FATP1 stimulated transport and consumption of palmitate and oleate, which they channeled away from complete oxidation and toward TAG synthesis. PMID: 15897321
- These data reveals the localization and points to a regulatory function of FATP1 in myotube mitochondria. PMID: 19361580
- Observational study of gene-disease association. (HuGE Navigator) PMID: 18660489
- Observational study of gene-disease association. (HuGE Navigator) PMID: 12818409
- Observational study of gene-disease association. (HuGE Navigator) PMID: 15978856
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亞細胞定位：Cell membrane; Single-pass membrane protein. Endomembrane system; Single-pass membrane protein. Cytoplasm.
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蛋白家族：ATP-dependent AMP-binding enzyme family
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組織特異性：Highest levels of expression are detected in muscle and adipose tissue small, intermediate levels in small intestine, and barely detectable in liver. Expressed in brain gray matter.
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數據庫鏈接：
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