SEC24A Antibody

說明書

產品詳情

Uniprot No.：

O95486
基因名：

SEC24A
別名：

SEC24A antibody; Protein transport protein Sec24A antibody; SEC24-related protein A antibody
宿主：

Rabbit
反應種屬：

Human,Mouse,Rat
免疫原：

Human SEC24A
免疫原種屬：

Homo sapiens (Human)
抗體亞型：

IgG
純化方式：

Antigen Affinity purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
產品提供形式：

Liquid
應用范圍：

ELISA,WB,IHC,IF
Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules for their transport to the Golgi complex. Plays a central role in cargo selection within the COPII complex and together with SEC24B may have a different specificity compared to SEC24C and SEC24D. May package preferentially cargos with cytoplasmic DxE or LxxLE motifs and may also recognize conformational epitopes.
基因功能參考文獻：
1. the association between Kv1.3 and the COPII cargo adaptor subunit isoform Sec24a PMID: 26156069
2. CstA, a secreted Brucella protein specifically interacts with human Sec24A. PMID: 22820839
3. Sec24 isoforms expand the repertoire of cargo for signal-mediated ER export, but are in part functionally redundant. PMID: 17255961
亞細胞定位：

Cytoplasmic vesicle, COPII-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytosol.
蛋白家族：

SEC23/SEC24 family, SEC24 subfamily
數據庫鏈接：

HGNC: 10703

OMIM: 607183

KEGG: hsa:10802

STRING: 9606.ENSP00000381823

UniGene: Hs.595540

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