SCARF2 Antibody

說明書

產品詳情

Uniprot No.：

Q96GP6
基因名：

SCARF2
別名：

SCARF2 antibody; SREC2 antibody; SREPCR antibody; Scavenger receptor class F member 2 antibody; SRECRP-1 antibody; Scavenger receptor expressed by endothelial cells 2 protein antibody; SREC-II antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Synthesized peptide derived from the Internal region of Human SREC-II.
免疫原種屬：

Homo sapiens (Human)
標記方式：

Non-conjugated
抗體亞型：

IgG
純化方式：

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
產品提供形式：

Liquid
應用范圍：

IHC, ELISA

推薦稀釋比：

Application	Recommended Dilution
IHC	1:100-1:300
ELISA	1:40000

Protocols：

Immunohistochemistry (IHC) Protocol
ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Probable adhesion protein, which mediates homophilic and heterophilic interactions. In contrast to SCARF1, it poorly mediates the binding and degradation of acetylated low density lipoprotein (Ac-LDL).
基因功能參考文獻：
1. the full VDEGS phenotype may include sclerocornea resulting from homozygosity or compound heterozygosity for loss of function variants in SCARF2. PMID: 24478002
2. Mutations in SCARF2 are responsible for Van Den Ende-Gupta syndrome. PMID: 20887961
3. SRECII binds to SRECI and has a similar tissue distribution pattern PMID: 12154095
相關疾病：

Van den Ende-Gupta syndrome (VDEGS)
亞細胞定位：

Membrane; Single-pass type I membrane protein.
組織特異性：

Predominantly expressed in endothelial cells. Expressed in heart, placenta, lung, kidney, spleen, small intestine and ovary.
數據庫鏈接：

HGNC: 19869

OMIM: 600920

KEGG: hsa:91179

STRING: 9606.ENSP00000266214

UniGene: Hs.474251

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