SCARA3 Antibody, FITC conjugated
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中文名稱：SCARA3兔多克隆抗體, FITC偶聯
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貨號：CSB-PA721489LC01HU
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規格：￥880
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其他：
產品詳情
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產品名稱：Rabbit anti-Homo sapiens (Human) SCARA3 Polyclonal antibody
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Uniprot No.：
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基因名：SCARA3
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別名：APC7 antibody; Cellular stress response antibody; Cellular stress response gene protein antibody; CSR antibody; CSR1 antibody; Macrophage scavenger receptor-like 1 antibody; MSLR1 antibody; MSRL1 antibody; SCAR3_HUMAN antibody; SCARA3 antibody; Scavenger receptor class A member 3 antibody
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宿主：Rabbit
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反應種屬：Human
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免疫原：Recombinant Human Scavenger receptor class A member 3 protein (201-466AA)
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免疫原種屬：Homo sapiens (Human)
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標記方式：FITC
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：Antigen Affinity Purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 -
產品提供形式：Liquid
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
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靶點詳情
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功能：Seems to protect cells by scavenging oxidative molecules or harmful products of oxidation.
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基因功能參考文獻：
- CSR1 is SUMOylated at K582 and rapid ubiquitinated and degradated in prostate cancer cells. PMID: 29705808
- demonstrated that CSR1 inhibited hepatocellular carcinoma cell proliferation, migration and invasion through inactivation of hematopoietic PBX interacting protein (HPIP) and its downstream PI3K/AKT signaling pathway. PMID: 28975986
- Suppression of CSR1 expression is a novel mechanism critical for the oncogenic activity of miR-650. PMID: 25956032
- Findings regarding the interaction of NADPH-P450 reductase (NPR) with cellular stress response (CSR) indicated function of NPR in hypoxic response. PMID: 24491563
- Data indicate that the clinical samples showed an inverse correlation between SCARA3 gene expression, myeloma progression, and favorable clinical prognosis. PMID: 23537707
- The binding of CSR1 with XIAP enhanced caspase-9 and caspase-3 protease activities. PMID: 22683311
- The consistently high SCARA3 levels in both primary carcinomas and metastatic cells in effusions, and its up-regulation along disease progression from diagnosis to recurrence, suggest a role in ovarian cancer biology. PMID: 21855113
- Results demonstrate the involvement of SCARA3 and SCARA5 in the uptake of PF14-oligonucleotide nanocomplexes. PMID: 22138034
- Down-regulation of CSR1 protein expression by promoter methylation is associated with tumor growth and metastasis of prostate cancer PMID: 16436673
- CSR1 appears to induce cell death through a novel mechanism by hijacking a critical RNA processing enzyme CPSF3. PMID: 18806823
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亞細胞定位：Endoplasmic reticulum membrane; Single-pass type II membrane protein. Golgi apparatus membrane; Single-pass type II membrane protein. Note=Endoplasmic reticulum and/or Golgi.
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組織特異性：Expressed ubiquitously.
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數據庫鏈接：
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