SCAMP2 Antibody

說明書

產品詳情

Uniprot No.：

O15127
基因名：

SCAMP2
別名：

SCAMP2; Secretory carrier-associated membrane protein 2; Secretory carrier membrane protein 2
宿主：

Rabbit
反應種屬：

Human,Mouse,Rat
免疫原：

Human SCAMP2
免疫原種屬：

Homo sapiens (Human)
抗體亞型：

IgG
純化方式：

Antigen Affinity purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
產品提供形式：

Liquid
應用范圍：

ELISA,WB,IHC
Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
Immunohistochemistry (IHC) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Functions in post-Golgi recycling pathways. Acts as a recycling carrier to the cell surface.
基因功能參考文獻：
1. this finding that SCAMP2 interacts with and regulates the subcellular distribution of both DAT and SERT suggests that interaction with SCAMP2 may constitute an important mechanism for coordinating cell surface expression of monoamine transporters. PMID: 21295544
2. SCAMP2 plays an important role in the regulation of the subcellular distribution of SERT PMID: 16870614
3. The strong correlation between SCAMP2 E interactions with PIP2 and inhibition of exocytosis, particularly by SC2-R204A, led us to propose that SCAMP2 interaction with PIP2 within the membrane interface regulates fusion pore formation during exocytosis. PMID: 17713930
4. SCAMP2 regulates NHE5 transit through recycling endosomes and promotes its surface targeting in an Arf6-dependent manner. PMID: 19276089
亞細胞定位：

Golgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein. Recycling endosome membrane; Multi-pass membrane protein.
蛋白家族：

SCAMP family
組織特異性：

Widely expressed.
數據庫鏈接：

HGNC: 10564

OMIM: 606912

KEGG: hsa:10066

STRING: 9606.ENSP00000268099

UniGene: Hs.458917

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