SAE1 Antibody
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中文名稱：SAE1兔多克隆抗體
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貨號：CSB-PA883359ESR2HU
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規格：￥440
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圖片：
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Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA883359ESR2HU at dilution of 1:100 -
Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA883359ESR2HU at dilution of 1:100
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其他：
產品詳情
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產品名稱：Rabbit anti-Homo sapiens (Human) SAE1 Polyclonal antibody
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Uniprot No.：
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基因名：
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別名：Activator of SUMO1 antibody; AOS1 antibody; HSPC140 antibody; Sae1 antibody; SAE1_HUMAN antibody; Sentrin/SUMO activating protein AOS1 antibody; SUA1 antibody; SUMO 1 activating enzyme E1 N subunit antibody; SUMO 1 activating enzyme subunit 1 antibody; SUMO-activating enzyme subunit 1 antibody; Ubiquitin like protein SUMO1 activating enzyme antibody; Ubiquitin-like 1-activating enzyme E1A antibody; UBL E1A antibody; UBLE1A antibody
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宿主：Rabbit
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反應種屬：Human
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免疫原：Recombinant Human SUMO-activating enzyme subunit 1 protein (1-346AA)
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：Antigen Affinity Purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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產品提供形式：Liquid
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應用范圍：ELISA, IHC
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推薦稀釋比：
Application Recommended Dilution IHC 1:20-1:200 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2.
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基因功能參考文獻：
- the expression of SENP8, SAE1, PIAS1, PIAS2 and ZMIZ1 is deregulated in the majority of PTC tissues, likely contributing to the PTC phenotype. PMID: 26403403
- as it has been shown by flow cytometry analysis, specific knockdown of SAE1 slowed down the cell population at G0/G1 phase and induced apoptosis of RKO cells. PMID: 25842831
- SUMO-1 controls the protein stability and the biological function of phosducin. PMID: 16421094
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亞細胞定位：Nucleus.
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蛋白家族：Ubiquitin-activating E1 family
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組織特異性：Expression level increases during S phase and drops in G2 phase (at protein level).
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數據庫鏈接：
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