RTN2 Antibody
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中文名稱：RTN2兔多克隆抗體
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貨號：CSB-PA020569GA01HU
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規格：￥3,900
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其他：
產品詳情
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Uniprot No.：
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基因名：RTN2
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別名：RTN2; NSPL1; Reticulon-2; Neuroendocrine-specific protein-like 1; NSP-like protein 1; Neuroendocrine-specific protein-like I; NSP-like protein I; NSPLI
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宿主：Rabbit
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反應種屬：Human,Mouse,Rat
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免疫原：Human RTN2
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免疫原種屬：Homo sapiens (Human)
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抗體亞型：IgG
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
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產品提供形式：Liquid
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應用范圍：ELISA,WB
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Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Inhibits amyloid precursor protein processing, probably by blocking BACE1 activity. Enhances trafficking of the glutamate transporter SLC1A1/EAAC1 from the endoplasmic reticulum to the cell surface. Plays a role in the translocation of SLC2A4/GLUT4 from intracellular membranes to the cell membrane which facilitates the uptake of glucose into the cell.
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基因功能參考文獻：
- Results implicate reticulon 2 in axonopathy, show that this protein participates in a network of interactions among hereditary spastic paraplegia proteins involved in endoplasmic reticulum shaping. PMID: 22232211
- Discusses cloning of mouse neuroendocrine-specific protein-like 1, in addition to partial cloning of the human ortholog. Also studies expression of both the mouse and human genes. PMID: 9530622
- RTN2B functions as a positive regulator in the delivery of EAAC1 from the ER to the cell surface. PMID: 18096700
- sk-NSPl1 is a novel dantrolene receptor that plays an important role in membrane translocation of GLUT4 induced by contraction/exercise. The 23-kDa sk-NSPl1 may also be involved in the regulation of glucose levels in the whole body. PMID: 19720795
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相關疾病：Spastic paraplegia 12, autosomal dominant (SPG12)
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亞細胞定位：Endoplasmic reticulum membrane; Multi-pass membrane protein. Sarcoplasmic reticulum membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Cell membrane, sarcolemma; Multi-pass membrane protein. Cell membrane, sarcolemma, T-tubule; Multi-pass membrane protein. Cytoplasm, myofibril, sarcomere, Z line. Cytoplasm, cytoskeleton.
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組織特異性：[Isoform RTN2-C]: Highly expressed in skeletal muscle.
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數據庫鏈接：
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