RHBDL2 Antibody

中文名稱：

RHBDL2兔多克隆抗體
貨號：

CSB-PA019672LA01HU
規格：

￥3900
圖片：
Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA019672LA01HU at dilution of 1:100
其他：

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) RHBDL2 Polyclonal antibody
Uniprot No.：

Q9NX52
基因名：

RHBDL2
別名：

RHBDL2 antibody; Rhomboid-related protein 2 antibody; RRP2 antibody; EC 3.4.21.105 antibody; Rhomboid-like protein 2) [Cleaved into: Rhomboid-related protein 2 antibody; N-terminal fragment antibody; NTF); Rhomboid-related protein 2 antibody; C-terminal fragment antibody; CTF)] antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Rhomboid-related protein 2 protein (12-132AA)
免疫原種屬：

Homo sapiens (Human)

標記方式：

Non-conjugated

本頁面中的產品，RHBDL2 Antibody (CSB-PA019672LA01HU)，的標記方式是Non-conjugated。對于RHBDL2 Antibody，我們還提供其他標記。見下表：

標記方式	貨號	產品名稱	應用
HRP	CSB-PA019672LB01HU	RHBDL2 Antibody, HRP conjugated	ELISA
FITC	CSB-PA019672LC01HU	RHBDL2 Antibody, FITC conjugated
Biotin	CSB-PA019672LD01HU	RHBDL2 Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA, IHC

推薦稀釋比：

Application	Recommended Dilution
IHC	1:20-1:200

Protocols：

ELISA Protocol
Immunohistochemistry (IHC) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Involved in regulated intramembrane proteolysis and the subsequent release of functional polypeptides from their membrane anchors. Known substrate: EFNB3.
基因功能參考文獻：
1. Thrombomodulin and RHBDL2 are upregulated in human HaCaT cells stimulated by scratch wounds; furthermore, increased solulbe thrombomodulin was found in culture medium. PMID: 21833011
2. RHBDL2 cleaves epidermal growth factor just outside its transmembrane domain, thereby facilitating its secretion and triggering activation of the epidermal growth factor receptor. PMID: 21494248
3. Substrate specificity of RHBDL2 intramembrane protease is governed by helix-breaking residues in the transmembrane domain. PMID: 12820957
4. Here, the authors show that RHBDL2 is produced as a proenzyme and that the processing of RHBDL2 is required for its cellular protease activity. PMID: 19850051
5. The encoded protein is thought to release soluble growth factors by proteolytic cleavage of certain membrane-bound substrates, including ephrin B2 and ephrin B3. PMID: 15047175
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亞細胞定位：

[Rhomboid-related protein 2, C-terminal fragment]: Cell membrane; Multi-pass membrane protein.
蛋白家族：

Peptidase S54 family
數據庫鏈接：

HGNC: 16083

OMIM: 608962

KEGG: hsa:54933

STRING: 9606.ENSP00000289248

UniGene: Hs.524626

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