RGS20 Antibody
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中文名稱：RGS20兔多克隆抗體
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貨號：CSB-PA019652GA01HU
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規格：￥3,900
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其他：
產品詳情
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Uniprot No.：
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基因名：RGS20
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別名：G(z)GAP antibody; Gz selective GTPase activating protein antibody; Gz-GAP antibody; Gz-selective GTPase-activating protein antibody; HGNC:14600 antibody; Regulator of G protein signaling 20 antibody; Regulator of G-protein signaling 20 antibody; Regulator of G-protein signaling Z1 antibody; Regulator of Gz selective protein signaling 1 antibody; Regulator of Gz-selective protein signaling 1 antibody; RGS20 antibody; RGS20_HUMAN antibody; RGSZ1 antibody; ZGAP1 antibody
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宿主：Rabbit
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反應種屬：Human,Mouse,Rat
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免疫原：Human RGS20
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免疫原種屬：Homo sapiens (Human)
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抗體亞型：IgG
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純化方式：Antigen Affinity Purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
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產品提供形式：Liquid
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應用范圍：ELISA,WB
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Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds selectively to G(z)-alpha and G(alpha)-i2 subunits, accelerates their GTPase activity and regulates their signaling activities. The G(z)-alpha activity is inhibited by the phosphorylation and palmitoylation of the G-protein. Negatively regulates mu-opioid receptor-mediated activation of the G-proteins.
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基因功能參考文獻：
- NEAT1 silencing also inhibited tumor growth in vivo. Collectively, we revealed that the NEAT1/miR365/RGS20 axis may be a novel mechanism or therapeutic strategy for OSCC treatment. PMID: 29484420
- Data suggest that Gpr176 (G-protein coupled receptor 176) is an SCN-(suprachiasmatic nucleus-)enriched orphan GPCR (G-protein-coupled receptor) that sets the pace of circadian behavior; a unique cAMP-repressing G-protein subclass Gz is required for the activity of Gpr176. [REVIEW] PMID: 28502923
- These results suggest that the expression of RGS20 may promote metastasis of tumor cells. PMID: 27495875
- Findings suggest that high regulator of G protein signaling 20 (RGS20) expression is associated with unfavorable survival in triple-negative breast cancer (TNBC). PMID: 28237701
- provide new evidence that RGSZ1 interacts not only with Galpha(z,) but also with Galpha(i), as supported by in vitro binding assays and functional studies PMID: 12379657
- NMR study PMID: 14872136
- The major function of PKCI-1 is to modulate mu opioid receptor signaling pathway along with RGSZ1, rather than directly mediating the Galphaz RGSZ1 interaction. PMID: 17126529
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亞細胞定位：Membrane; Lipid-anchor. Nucleus. Cytoplasm.
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組織特異性：Isoform 5 is expressed in brain at high levels in the caudate nucleus and temporal lobe.
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數據庫鏈接：
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