RGS13 Antibody
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中文名稱：RGS13兔多克隆抗體
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貨號(hào)：CSB-PA019645GA01HU
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規(guī)格：￥3,900
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其他：
產(chǎn)品詳情
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Uniprot No.：
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基因名：RGS13
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別名：AL713991.1 antibody; HGNC:9995 antibody; MGC17173 antibody; OTTMUSP00000022853 antibody; OTTMUSP00000022854 antibody; Regulator of G protein signalling 13 antibody; Regulator of G-protein signaling 13 antibody; RGD1562103 antibody; RGS 13 antibody; RGS13 antibody; RGS13_HUMAN antibody; RP11 92K2.1 antibody
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宿主：Rabbit
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反應(yīng)種屬：Human,Mouse,Rat
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免疫原：Human RGS13
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免疫原種屬：Homo sapiens (Human)
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抗體亞型：IgG
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純化方式：Antigen Affinity Purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
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產(chǎn)品提供形式：Liquid
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應(yīng)用范圍：ELISA,IHC
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Protocols：
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儲(chǔ)存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
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靶點(diǎn)詳情
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功能：Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to both G(i)-alpha and G(q)-alpha.
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基因功能參考文獻(xiàn)：
- p53 may modulate immune responses through suppression of RGS13 transcription in mast cells and B cells PMID: 21531726
- RGS13 turnover was significantly reduced in cells stimulated with cAMP, which was reversed by expression of the PKA-specific inhibitory peptide PKI. PMID: 20974683
- Functional characterization of the G protein regulator RGS13 PMID: 11875076
- Down-Regulation of regulator of G-protein signalling 13 is associated with mantle cell lymphoma PMID: 12970790
- RGS13 overexpression inhibited CXCL12-evoked Ca(2+) mobilization, Akt phosphorylation and chemotaxis. PMID: 19017978
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