RGL2 Antibody, Biotin conjugated

說明書

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) RGL2 Polyclonal antibody
Uniprot No.：

O15211
基因名：

RGL2
別名：

GDS related protein antibody; HKE1.5 antibody; KE1.5 antibody; RAB2L antibody; Ral guanine nucleotide dissociation stimulator-like 2 antibody; RalGDS-like 2 antibody; RalGDS-like factor antibody; Ras-associated protein RAB2L antibody; RGL2 antibody; RGL2_HUMAN antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Ral guanine nucleotide dissociation stimulator-like 2 protein (145-328AA)
免疫原種屬：

Homo sapiens (Human)
標記方式：

Biotin
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA
Protocols：

ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Probable guanine nucleotide exchange factor. Putative effector of Ras and/or Rap. Associates with the GTP-bound form of Rap 1A and H-Ras in vitro.
基因功能參考文獻：
1. SAMD9, an IFN-gamma-responsive protein, interacts with RGL2 to diminish the expression of EGR1, a protein of direct relevance to the pathogenesis of ectopic calcification and inflammation. PMID: 21160498
2. Rgl2 and RalB both localized to the leading edge, and this localization of RalB was dependent on endogenous Rgl2 expression. PMID: 20801877
3. RGL2 is phosphorylated by PKA and phosphorylation reduces the ability of RGL2 to bind H-Ras. results of the present study indicate that Ras may distinguish between the different RalGDS family members by their phosphorylation by PKA. PMID: 18540861
數據庫鏈接：

HGNC: 9769

OMIM: 602306

KEGG: hsa:5863

STRING: 9606.ENSP00000420211

UniGene: Hs.509622

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