Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期:
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途:
For Research Use Only. Not for use in diagnostic or therapeutic procedures.
May repress E2F-dependent transcription. May promote AR-dependent transcription.
基因功能參考文獻:
Studies indicate that data on the regulatory functions of the KRAB-ZFP in embryonic development and tumorgenesis will benefit the understanding of biological roles of KRAB-ZFP in different physiological and pathological states. PMID: 20466629
RBaK interacts with the androgen receptor and increases its transcriptional activity. PMID: 14664718
study found no evidence of mutations in the coding sequence and splice sites of RBaK in association with familial hyperaldosteronism type II PMID: 17121540
The role of RBaK, PMS2, and GNA12 in the inheritance of familial hyperaldosteronism type II were studied. PMID: 18307725
亞細胞定位:
Nucleus.
蛋白家族:
Krueppel C2H2-type zinc-finger protein family
組織特異性:
Expressed in bone, brain, heart, kidney, liver, lung, pancreas and placenta.