Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期:
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用途:
For Research Use Only. Not for use in diagnostic or therapeutic procedures.
May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
基因功能參考文獻:
This is the first study that identifies a new Rab40b-Tks5- and miR-204-dependent invadopodia transport pathway that regulates MMP2 and MMP9 secretion, and extracellular matrix remodeling during cancer progression. PMID: 27789576
High expression level of Rab40b was significantly correlated with gastric cancer invasion and lymph node metastasis. PMID: 25790780
Rab40b mediates trafficking of MMP2/9 during invadopodia formation and metastasis of breast cancer cells. PMID: 23902685