RAB11FIP5 Antibody, Biotin conjugated
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中文名稱：RAB11FIP5兔多克隆抗體, Biotin偶聯
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貨號：CSB-PA863141LD01HU
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規格：￥880
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其他：
產品詳情
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產品名稱：Rabbit anti-Homo sapiens (Human) RAB11FIP5 Polyclonal antibody
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Uniprot No.：
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基因名：
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別名：GAF 1 antibody; Gaf-1 antibody; GAF1 antibody; gamma SNAP associated factor 1 antibody; Gamma-SNAP-associated factor 1 antibody; KIAA0857 antibody; Phosphoprotein pp75 antibody; pp75 antibody; RAB11 family interacting protein 5 (class I) antibody; Rab11 family-interacting protein 5 antibody; Rab11 FIP5 antibody; Rab11 interacting protein antibody; Rab11 interacting protein Rip11 antibody; Rab11-FIP5 antibody; Rab11-interacting protein Rip11 antibody; Rab11fip5 antibody; RFIP5_HUMAN antibody; RIP11 antibody
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宿主：Rabbit
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反應種屬：Human
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免疫原：Recombinant Human Rab11 family-interacting protein 5 protein (374-545AA)
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免疫原種屬：Homo sapiens (Human)
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標記方式：Biotin
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：>95%, Protein G purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 -
產品提供形式：Liquid
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應用范圍：ELISA
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Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
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靶點詳情
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功能：Rab effector involved in protein trafficking from apical recycling endosomes to the apical plasma membrane. Involved in insulin granule exocytosis. May regulate V-ATPase intracellular transport in response to extracellular acidosis.
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基因功能參考文獻：
- FIP5-T276 phosphorylation occurs specifically during metaphase and anaphase. PMID: 24591568
- FIP5-SNX18 complex plays a pivotal role in the polarized transport of apical proteins during apical lumen initiation in epithelial cells. PMID: 21969467
- These data introduce Rab11b as a crucial regulator and Rip11 as mediator of acidosis-induced V-ATPase traffic in duct cells of submandibular gland. PMID: 20717956
- analysis of the rearrangement breakpoints suggests that the reciprocal translocation may have formed secondary to incorrect repair of double strand breaks (DSBs) by nonhomologous end-joining (NHEJ). PMID: 18384058
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亞細胞定位：Cytoplasm. Recycling endosome membrane; Peripheral membrane protein. Early endosome membrane; Peripheral membrane protein. Golgi apparatus membrane; Peripheral membrane protein. Cytoplasmic vesicle, secretory vesicle membrane; Peripheral membrane protein. Mitochondrion membrane; Peripheral membrane protein.
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組織特異性：Detected at low levels in heart, brain, placenta, lung, liver, adipocytes, kidney, spleen, skeletal muscle and pancreas.
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數據庫鏈接：
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