QPRT Antibody
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中文名稱：QPRT兔多克隆抗體
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貨號：CSB-PA621868LA01HU
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規格：￥440
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圖片：
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IHC image of CSB-PA621868LA01HU diluted at 1:300 and staining in paraffin-embedded human liver cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. -
Immunofluorescence staining of HepG2 cells with CSB-PA621868LA01HU at 1:100, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
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其他：
產品詳情
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產品名稱：Rabbit anti-Homo sapiens (Human) QPRT Polyclonal antibody
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Uniprot No.：
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基因名：QPRT
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別名：NADC_HUMAN antibody; Nicotinate nucleotide pyrophosphorylase (carboxylating) antibody; Nicotinate-nucleotide pyrophosphorylase [carboxylating] antibody; QAPRTase antibody; QPRT antibody; QPRTase antibody; Quinolinate phosphoribosyltransferase [decarboxylating] antibody; Quinolinate phosphoribosyltransferase antibody
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宿主：Rabbit
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反應種屬：Human
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免疫原：Recombinant Human Nicotinate-nucleotide pyrophosphorylase [carboxylating] protein (113-254AA)
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
本頁面中的產品，QPRT Antibody (CSB-PA621868LA01HU)，的標記方式是Non-conjugated。對于QPRT Antibody，我們還提供其他標記。見下表：
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：>95%, Protein G purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 -
產品提供形式：Liquid
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應用范圍：ELISA, IHC, IF
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推薦稀釋比：
Application Recommended Dilution IHC 1:200-1:500 IF 1:50-1:200 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Involved in the catabolism of quinolinic acid (QA).
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基因功能參考文獻：
- Our data suggest that QPRT may play an important role in the pathogenesis of autism spectrum disorders in Chr16p11.2 deletion carriers. PMID: 30443311
- WT1 knock-down gave a corresponding decrease in QPRT gene and protein expression. Chromatin-immunoprecipitation revealed WT1 binding to a conserved site in the first intron of the QPRT gene. PMID: 27889611
- The structural features, size distribution, heat aggregation and ITC studies of the full-length enzyme and the enzyme lacking helix alpha1 strongly suggest that human QPRT acts as a hexamer for cooperative reactant binding via three dimeric subunits and maintaining stability. PMID: 26805589
- Report of the crystal structure of human QPRT bound to its inhibitor phthalic acid (PHT) and kinetic analysis of PHT inhibition of human QPRT. PMID: 24038671
- QPRT is a potential new marker for the immunohistochemical screening of follicular thyroid nodules. PMID: 19321014
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蛋白家族：NadC/ModD family
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數據庫鏈接：
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