PTPN9 Antibody, HRP conjugated
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中文名稱：PTPN9兔多克隆抗體, HRP偶聯
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貨號：CSB-PA019045LB01HU
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規格：￥880
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其他：
產品詳情
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產品名稱：Rabbit anti-Homo sapiens (Human) PTPN9 Polyclonal antibody
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Uniprot No.：
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基因名：PTPN9
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別名：MEG2 antibody; non-receptor type 9 antibody; protein tyrosine phosphatase antibody; Protein tyrosine phosphatase MEG2 antibody; Protein-tyrosine phosphatase MEG2 antibody; PTN9_HUMAN antibody; PTPase MEG2 antibody; Ptpn9 antibody; Tyrosine protein phosphatase non receptor type 9 antibody; Tyrosine-protein phosphatase non-receptor type 9 antibody
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宿主：Rabbit
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反應種屬：Human
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免疫原：Recombinant Human Tyrosine-protein phosphatase non-receptor type 9 protein (221-339AA)
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免疫原種屬：Homo sapiens (Human)
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標記方式：HRP
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：>95%, Protein G purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 -
產品提供形式：Liquid
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應用范圍：ELISA
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Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Protein-tyrosine phosphatase that could participate in the transfer of hydrophobic ligands or in functions of the Golgi apparatus.
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基因功能參考文獻：
- Results from a study on gene expression variability markers in early-stage human embryos shows that PTPN9 is a putative expression variability marker for the 3-day, 8-cell embryo stage. PMID: 26288249
- this study highlights an important role for miR-96 in the regulation of PTPN9 in breast cancer cells and may provide insight into the molecular mechanisms of breast carcinogenesis. PMID: 27857177
- Expression of MEG2 is reversely correlated with that of miR-181a-5p in gastric cancer. PMID: 28747184
- PTPN9 inhibited cell proliferation in HepG2 cells. PMID: 26715439
- PTPMeg2 is an important phosphatase for the dephosphorylation of STAT3 and plays a critical role in breast cancer development. PMID: 22394684
- This study indentified VEGFR2 as a PTPN9 substrate, and indicated that PTPN9 is a negative regulator of VEGFR2 signaling and function in endothelial cells. PMID: 22763125
- data suggest PTPN9 as a negative regulator of breast cancer cells by targeting ErbB2 and EGFR and inhibiting STAT activation PMID: 20335174
- Purification and characterization of protein tyrosine phosphatase PTP-MEG2 PMID: 12112018
- PTP-MEG2 has an important role in the development of erythroid cells. PMID: 12920026
- PTPase-MEG2 through its Sec14p homology domain couples inositide phosphorylation to tyrosine dephosphorylation and the regulation of intracellular traffic of the secretory pathway in T cells. PMID: 14662869
- PTP-MEG2 reduced the phosphotyrosine content of NSF and co-localized with NSF and syntaxin 6 in intact cells, the first demonstrated role for a protein tyrosine phosphatase in the regulated secretory pathway PMID: 15322554
- role in the negative regulation of hepatic insulin signaling PMID: 16679294
- the N terminus of PTPMEG2 is necessary for the targeting of this phosphatase to the secretory vesicle compartment by association with other proteins involved in intracellular transport. PMID: 17387180
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亞細胞定位：Cytoplasm.
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蛋白家族：Protein-tyrosine phosphatase family, Non-receptor class 3 subfamily
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數據庫鏈接：
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