PRKAB2 Antibody
-
中文名稱：PRKAB2兔多克隆抗體
-
貨號：CSB-PA652945
-
規格：￥1090
-
圖片：
-
Western blot analysis of 1) 293T, 2) HepG2, 3) Mouse Heart Tissue, 4) Rat Heart Tissue using AMPKβ2 Polyclonal Antibody.
-
-
其他：
產品詳情
-
Uniprot No.：
-
基因名：
-
別名：5' AMP activated protein kinase beta 2 subunit antibody; 5' AMP activated protein kinase subunit beta 2 antibody; 5''-AMP-activated protein kinase subunit beta-2 antibody; AAKB2_HUMAN antibody; AMP activated protein kinase beta 2 non catalytic subunit antibody; AMPK beta 2 antibody; AMPK beta 2 chain antibody; AMPK subunit beta 2 antibody; AMPK subunit beta-2 antibody; MGC61468 antibody; PRKAB 2 antibody; Prkab2 antibody; Protein kinase AMP activated beta 2 non catalytic subunit antibody
-
宿主：Rabbit
-
反應種屬：Human,Mouse,Rat
-
免疫原：Recombinant Protein
-
免疫原種屬：Homo sapiens (Human)
-
標記方式：Non-conjugated
-
抗體亞型：IgG
-
濃度：It differs from different batches. Please contact us to confirm it.
-
保存緩沖液：PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
-
產品提供形式：Liquid
-
應用范圍：WB
-
推薦稀釋比：
Application Recommended Dilution WB 1:1000-2000 -
Protocols：
-
儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
-
用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
-
功能：Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3).
-
基因功能參考文獻：
- Sumoylation of AMPKbeta2 subunit enhances AMP-activated protein kinase activity. PMID: 23552691
- results of this study demonistrated that the novel findings that intronic SNPs in the genes coding for the regulatory beta2(PRKAB2) of AMPK are associated with antipsychotic-induced weight gain in schizophrenia or schizoaffective disorder patients PMID: 22305490
- variants in PRKAB2 are unlikely to contribute to the type 2 diabetes mellitus susceptibility in Pima Indians PMID: 12490143
-
蛋白家族：5'-AMP-activated protein kinase beta subunit family
-
數據庫鏈接：
Most popular with customers
-
-
YWHAB Recombinant Monoclonal Antibody
Applications: ELISA, WB, IHC, IF, FC
Species Reactivity: Human, Mouse, Rat
-
Phospho-YAP1 (S127) Recombinant Monoclonal Antibody
Applications: ELISA, WB, IHC
Species Reactivity: Human
-
-
-
-
-
