PPM1L Antibody
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中文名稱：PPM1L兔多克隆抗體
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貨號：CSB-PA007469
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規格：￥1090
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圖片：
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Western Blot analysis of Jurkat cells using PP2Cε Polyclonal Antibody
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其他：
產品詳情
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Uniprot No.：
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基因名：PPM1L
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別名：PPM1L antibody; PP2CE antibody; Protein phosphatase 1L antibody; EC 3.1.3.16 antibody; Protein phosphatase 1-like antibody; Protein phosphatase 2C isoform epsilon antibody; PP2C-epsilon antibody
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宿主：Rabbit
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反應種屬：Human,Mouse,Rat
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免疫原：Synthesized peptide derived from the Internal region of Human PP2Cε.
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
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抗體亞型：IgG
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純化方式：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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產品提供形式：Liquid
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應用范圍：WB, ELISA
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推薦稀釋比：
Application Recommended Dilution WB 1:500-1:2000 ELISA 1:10000 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Acts as a suppressor of the SAPK signaling pathways by associating with and dephosphorylating MAP3K7/TAK1 and MAP3K5, and by attenuating the association between MAP3K7/TAK1 and MAP2K4 or MAP2K6.
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基因功能參考文獻：
- Genetic variation at chromosome 3 harbors an element that regulates expression of an upstream candidate tumor suppressor, PPM1L, thus providing a novel mechanism for colorectal tumorigenesis. PMID: 19847890
- cloning and characterization of a novel human protein phosphatase 2C cDNA (PP2C epsilon*) PMID: 15560375
- These results suggest that PP2Cepsilon maintains ASK1 in an inactive state by dephosphorylation in quiescent cells, supporting the possibility that PP2Cepsilon and PP5 play different roles in H2O2-induced regulation of ASK1 activity. PMID: 17456047
- CERT is a physiological substrate of PP2Cepsilon and that dephosphorylation of CERT by PP2Cepsilon may play an important role in the regulation of ceramide trafficking from the ER to the Golgi apparatus. PMID: 18165232
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亞細胞定位：Membrane; Single-pass type I membrane protein.
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蛋白家族：PP2C family
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組織特異性：Ubiquitous. Highly expressed in heart, placenta, lung, liver, kidney and pancreas.
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數據庫鏈接：
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