PPIF Antibody
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中文名稱：PPIF兔多克隆抗體
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貨號：CSB-PA018476ESR2HU
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規格：￥440
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圖片：
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Immunohistochemistry of paraffin-embedded human heart tissue using CSB-PA018476ESR2HU at dilution of 1:100
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其他：
產品詳情
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產品名稱：Rabbit anti-Homo sapiens (Human) PPIF Polyclonal antibody
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Uniprot No.：
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基因名：
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別名：Cyclophilin 3 antibody; cyclophilin D antibody; Cyclophilin F antibody; Cyp D antibody; CyP M antibody; CyP-D antibody; CyP-M antibody; CYP3 antibody; CypD antibody; hCyP3 antibody; mitochondrial antibody; Mitochondrial cyclophilin antibody; Peptidyl prolyl cis trans isomerase, mitochondral antibody; Peptidyl-prolyl cis-trans isomerase F antibody; Peptidyl-prolyl cis-trans isomerase F, mitochondrial antibody; Peptidylprolyl isomerase F (cyclophilin F) antibody; Peptidylprolyl isomerase F antibody; PPIase antibody; PPIase F antibody; Ppif antibody; PPIF_HUMAN antibody; Rotamase antibody; Rotamase F antibody
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宿主：Rabbit
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反應種屬：Human
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免疫原：Recombinant Human Peptidyl-prolyl cis-trans isomerase F, mitochondrial protein (30-207AA)
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：Antigen Affinity Purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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產品提供形式：Liquid
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應用范圍：ELISA, IHC
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推薦稀釋比：
Application Recommended Dilution IHC 1:20-1:200 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：PPIase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and may therefore assist protein folding. Involved in regulation of the mitochondrial permeability transition pore (mPTP). It is proposed that its association with the mPTP is masking a binding site for inhibiting inorganic phosphate (Pi) and promotes the open probability of the mPTP leading to apoptosis or necrosis; the requirement of the PPIase activity for this function is debated. In cooperation with mitochondrial p53/TP53 is involved in activating oxidative stress-induced necrosis. Involved in modulation of mitochondrial membrane F(1)F(0) ATP synthase activity and regulation of mitochondrial matrix adenine nucleotide levels. Has anti-apoptotic activity independently of mPTP and in cooperation with BCL2 inhibits cytochrome c-dependent apoptosis.
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基因功能參考文獻：
- Cyclophilin D protects cell from cell death. PMID: 12077116
- There was increased [Ca(2+)](c), [Ca(2+)](m), mCICR, MPTP opening, and expression of cyclophilin D and decreased DeltaPsim in POAG TM cells compared with control cells. PMID: 18614807
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亞細胞定位：Mitochondrion matrix.
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蛋白家族：Cyclophilin-type PPIase family
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數據庫鏈接：
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