POLR2J Antibody

說明書

產品詳情

Uniprot No.：

P52435
基因名：

POLR2J
別名：

DNA directed RNA polymerase II subunit RPB11 a antibody; DNA-directed RNA polymerase II 13.3 kDa polypeptide antibody; DNA-directed RNA polymerase II 13.3 kDa polypeptide antibody; DNA-directed RNA polymerase II subunit J 1 antibody; DNA-directed RNA polymerase II subunit J-1 antibody; DNA-directed RNA polymerase II subunit RPB11-a antibody; hRPB 14 antibody; hRPB14 antibody; POLR 2J1 antibody; POLR2J antibody; POLR2J1 antibody; polymerase (RNA) II (DNA directed) polypeptide J 13.3kDa antibody; polymerase (RNA) II (DNA directed) polypeptide J 13.3kDa antibody; RNA polymerase II 13.3 kDa subunit antibody; RNA polymerase II subunit B11 a antibody; RNA polymerase II subunit B11-a antibody; RPB 11 antibody; RPB 11A antibody; RPB 11m antibody; RPB11 antibody; RPB11_HUMAN antibody; RPB11a antibody; RPB11m antibody; Rpo2-4 antibody
宿主：

Rabbit
反應種屬：

Human,Mouse
免疫原：

Synthesized peptide derived from the N-terminal region of Human POLR2J1.
免疫原種屬：

Homo sapiens (Human)
標記方式：

Non-conjugated
抗體亞型：

IgG
純化方式：

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
產品提供形式：

Liquid
應用范圍：

WB, ELISA

推薦稀釋比：

Application	Recommended Dilution
WB	1:500-1:2000
ELISA	1:40000

Protocols：

Western Blotting (WB) Protocol
ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB11 is part of the core element with the central large cleft.
基因功能參考文獻：
1. POLR2J interacts with three different subunits of eIF3, eIF3a, eIF3i, and eIF3m. PMID: 22022972
2. Four independent genes(POLR2J1, POLR2J2, POLR2J3, POLR2J4) encoding various variants of the hRPB11 subunit of Homo sapiens RNA polymerase II were revealed in human chromosome 7 PMID: 15586814
亞細胞定位：

Nucleus.
蛋白家族：

Archaeal RpoL/eukaryotic RPB11/RPC19 RNA polymerase subunit family
組織特異性：

Ubiquitously expressed. High expression was found in heart and skeletal muscle.
數據庫鏈接：

HGNC: 9197

OMIM: 604150

KEGG: hsa:5439

STRING: 9606.ENSP00000292614

UniGene: Hs.654952

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