PMP2 Antibody
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中文名稱：PMP2兔多克隆抗體
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貨號：CSB-PA018240GA01HU
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規格：￥3,900
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其他：
產品詳情
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Uniprot No.：
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基因名：PMP2
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別名：FABP8 antibody; M FABP antibody; MP2 antibody; Myelin FABP antibody; Myelin P2 protein antibody; MYP2_HUMAN antibody; P2 antibody; Peripheral myelin protein 2 antibody; PMP2 antibody
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宿主：Rabbit
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反應種屬：Human,Mouse,Rat
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免疫原：Human PMP2
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免疫原種屬：Homo sapiens (Human)
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抗體亞型：IgG
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純化方式：Antigen Affinity Purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
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產品提供形式：Liquid
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應用范圍：ELISA,WB,IHC
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Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：May play a role in lipid transport protein in Schwann cells. May bind cholesterol.
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基因功能參考文獻：
- The structural characterization of the F57A mutant of P2 which shows changes in the portal region and helix alpha2 and an unfolded status upon lipid bilayer binding. Further results suggest a central role for Phe57 in regulating the opening of the portal region in human P2, and the F57A mutation disturbs dynamic cross-correlation networks in the portal region of P2. PMID: 29940944
- SH3TC2, PMP2, and BSCL2 pathogenic variants might be rare in Chinese Charcot-Marie-Tooth (CMT) patients. PMID: 29336362
- Our genetic and clinical findings in these kindred demonstrate that dominant PMP2 mutations cause Charcot-Marie- Tooth disease type 1. PMID: 27009151
- A fully deuterated sample of myelin P2 protein was produced identifying the neutron crystal structure. PMID: 26527266
- This report might expand the genetic and clinical features of Charcot-Marie-Tooth disease and a further mechanism study will enhance our understanding of PMP2-associated peripheral neuropathy. PMID: 26828946
- The structure of human P2 refined at the ultrahigh resolution of 0.93 A allows detailed structural analyses, including the full organization of an internal hydrogen-bonding network. PMID: 24419389
- the structure and function of the P2 protein from human myelin, which is able to bind both monomeric lipids inside its cavity and membrane surfaces PMID: 20421974
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亞細胞定位：Cytoplasm.
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蛋白家族：Calycin superfamily, Fatty-acid binding protein (FABP) family
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數據庫鏈接：
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