PLEKHF2 Antibody
-
中文名稱：PLEKHF2兔多克隆抗體
-
貨號：CSB-PA884492ESR1HU
-
規(guī)格：￥440
-
圖片：
-
Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA884492ESR1HU at dilution of 1:100
-
-
其他：
產(chǎn)品詳情
-
產(chǎn)品名稱：Rabbit anti-Homo sapiens (Human) PLEKHF2 Polyclonal antibody
-
Uniprot No.：
-
基因名：
-
別名：110070J07Rik antibody; AA673237 antibody; FLJ13187 antibody; PH and FYVE domain containing protein 2 antibody; PH and FYVE domain-containing protein 2 antibody; PH domain containing family F member 2 antibody; PH domain-containing family F member 2 antibody; Phafin 2 antibody; Phafin-2 antibody; PHAFIN2 antibody; PKHF2_HUMAN antibody; pleckstrin homology domain containing, family F (with FYVE domain) member 2 antibody; pleckstrin homology domain containing, family F (with FYVE domain) member2 antibody; Pleckstrin homology domain-containing family F member 2 antibody; Plekhf2 antibody; ZFYVE18 antibody; Zinc finger FYVE domain containing protein 18 antibody; Zinc finger FYVE domain-containing protein 18 antibody
-
宿主：Rabbit
-
反應(yīng)種屬：Human
-
免疫原：Recombinant Human Pleckstrin homology domain-containing family F member 2 protein (1-249AA)
-
免疫原種屬：Homo sapiens (Human)
-
標(biāo)記方式：Non-conjugated
-
克隆類型：Polyclonal
-
抗體亞型：IgG
-
純化方式：Antigen Affinity Purified
-
濃度：It differs from different batches. Please contact us to confirm it.
-
保存緩沖液：PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
-
產(chǎn)品提供形式：Liquid
-
應(yīng)用范圍：ELISA, IHC
-
推薦稀釋比：
Application Recommended Dilution IHC 1:20-1:200 -
Protocols：
-
儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
-
用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產(chǎn)品評價(jià)
相關(guān)產(chǎn)品
靶點(diǎn)詳情
-
功能：May play a role in early endosome fusion upstream of RAB5, hence regulating receptor trafficking and fluid-phase transport. Enhances cellular sensitivity to TNF-induced apoptosis.
-
基因功能參考文獻(xiàn)：
- PtdIns(3)P binding to Phafin2 occurs with high affinity, triggering minor conformational changes in the protein. Taken together, these studies represent a platform for establishing the structural basis of Phafin2 molecular interactions and the role of the two potentially redundant PtdIns(3)P-binding domains of the protein in endomembrane compartments. PMID: 28152563
- These findings establish that lysosomal accumulation of Akt and Phafin2 is a critical step in the induction of autophagy via an interaction with phosphatidylinositol 3 phosphate. PMID: 24416124
- Phafin2 controls EGFR trafficking through early endosomes by facilitating endosome fusion in concert with EEA1. PMID: 22816767
- These results provide a vivid example that an endosome modulator, such as Phafin2, may control the cells' responses to the extracellular cues. PMID: 19995552
- Results demonstrate that EAPF/Phafin-2 facilitates TNF-alpha-induced cellular apoptosis through an ER-mitochondrial apoptotic pathway. PMID: 18288467
顯示更多
收起更多
-
亞細(xì)胞定位：Early endosome membrane; Peripheral membrane protein. Endoplasmic reticulum.
-
組織特異性：Expressed in placenta, ovary and small intestine, as well as in heart and pancreas. Also expressed in peripheral blood mononuclear cells and dendritic cells.
-
數(shù)據(jù)庫鏈接：
Most popular with customers
-
YWHAB Recombinant Monoclonal Antibody
Applications: ELISA, WB, IHC, IF, FC
Species Reactivity: Human, Mouse, Rat
-
Phospho-YAP1 (S127) Recombinant Monoclonal Antibody
Applications: ELISA, WB, IHC
Species Reactivity: Human
-
-
-
-
-
-
