PHKB Antibody

說明書

產品詳情

Uniprot No.：

Q93100
基因名：

PHKB
別名：

DKFZp781E15103 antibody; FLJ41698 antibody; KPBB_HUMAN antibody; PHKB antibody; Phosphorylase b kinase regulatory subunit beta antibody; Phosphorylase kinase B antibody; Phosphorylase kinase beta polypeptide antibody; Phosphorylase kinase beta subunit antibody; Phosphorylase kinase subunit beta antibody
宿主：

Rabbit
反應種屬：

Human,Mouse
免疫原：

Synthesized peptide derived from the Internal region of Human PHKB.
免疫原種屬：

Homo sapiens (Human)
標記方式：

Non-conjugated
抗體亞型：

IgG
純化方式：

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
產品提供形式：

Liquid
應用范圍：

WB, ELISA

推薦稀釋比：

Application	Recommended Dilution
WB	1:500-1:2000
ELISA	1:40000

Protocols：

Western Blotting (WB) Protocol
ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. The beta chain acts as a regulatory unit and modulates the activity of the holoenzyme in response to phosphorylation.
基因功能參考文獻：
1. PHKb affects colorectal cancer cell growth and represents a novel prognostic biomarker. PMID: 28275865
2. Analysis showed that the glycogen phosphorylase kinase beta-subunit (PHKB) interacted with the C-terminal region of KIAA1199 protein. PMID: 25051373
相關疾病：

Glycogen storage disease 9B (GSD9B)
亞細胞定位：

Cell membrane; Lipid-anchor; Cytoplasmic side.
蛋白家族：

Phosphorylase b kinase regulatory chain family
數據庫鏈接：

HGNC: 8927

OMIM: 172490

KEGG: hsa:5257

STRING: 9606.ENSP00000313504

UniGene: Hs.78060

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