PFKP Antibody
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中文名稱(chēng)：PFKP兔多克隆抗體
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貨號(hào)：CSB-PA082915
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規(guī)格：￥2024
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圖片：
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Western blot analysis of extracts from COS-7 cells and A549 cells, using K6PP antibody.
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其他：
產(chǎn)品詳情
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產(chǎn)品名稱(chēng)：Rabbit anti-Homo sapiens (Human) PFKP Polyclonal antibody
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Uniprot No.：
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基因名：
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宿主：Rabbit
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反應(yīng)種屬：Human,Mouse,Rat
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免疫原：Synthesized peptide derived from internal of Human K6PP.
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免疫原種屬：Homo sapiens (Human)
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克隆類(lèi)型：Polyclonal
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純化方式：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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濃度：It differs from different batches. Please contact us to confirm it.
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產(chǎn)品提供形式：Liquid
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應(yīng)用范圍：ELISA,WB
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推薦稀釋比：
Application Recommended Dilution WB 1:500-1:3000 -
Protocols：
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儲(chǔ)存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產(chǎn)品評(píng)價(jià)
相關(guān)產(chǎn)品
靶點(diǎn)詳情
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功能：Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
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基因功能參考文獻(xiàn)：
- Snail functions as a metabolic switch between aerobic glycolysis and pentose phosphate pathway by repressing PFKP, a cancer-specific PFK-1, allowing cancer cell survival under metabolic stress. PMID: 28176759
- Here the authors show that PFK1 platelet isoform is upregulated in Glioblastoma and is required for tumor growth mechanistically, such upregulation is due to an increased stability induced by AKT activation via phosphorylation on residue S386. PMID: 29038421
- Data indicate that platelet isoform of phosphofructokinase (PFKP) not only is required for metabolic reprogramming and maintaining cell proliferation, but also may be a valid target for anti-renal cancer pharmaceutical agents. PMID: 27049827
- The crystallized PFKP is permanently activated by a deletion of the 22 C-terminal residues. PMID: 26205495
- Anti-human protein S antibody induces tissue factor expression through a direct interaction with PFKP and ERK1/2 activation in coronary artery endothelial cells. PMID: 24331211
- expression of TARDBP is significantly elevated in HCC and it regulates the expression of PFKP, the rate-limiting enzyme for glycolysis, through negative regulation of microRNA 520s (miR-520s). PMID: 23389994
- KLF4 plays a role in maintenance of high glycolytic metabolism by transcriptional activation of the PFKP gene in breast cancer cells. PMID: 21586797
- PFKP was identified using a trifunctional phenyl sulfonate probe. PMID: 12438565
- The transcription start point was determined at 48 bp upstream of the start codon. the region -65 to +48 turned out to be sufficient for promoter activity PMID: 15716112
- PFKP polymorphisms play no apparent role in the development of common forms of obesity in the Danish population. PMID: 18682847
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亞細(xì)胞定位：Cytoplasm.
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蛋白家族：Phosphofructokinase type A (PFKA) family, ATP-dependent PFK group I subfamily, Eukaryotic two domain clade "E" sub-subfamily
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數(shù)據(jù)庫(kù)鏈接：
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