PAXBP1 Antibody

說明書

產品詳情

Uniprot No.：

Q9Y5B6
基因名：

PAXBP1
別名：

BM 020 antibody; BM020 antibody; Chromosome 21 open reading frame 66 antibody; FSAP105 antibody; Functional spliceosome-associated protein 105 antibody; GC rich sequence DNA binding factor candidate antibody; GC-rich sequence DNA-binding factor 1 antibody; GCFC antibody; GCFC1 antibody; GCFC1_HUMAN antibody; PAX3 and PAX7 binding protein 1 antibody; PAXBP1 antibody
宿主：

Rabbit
反應種屬：

Human,Mouse,Rat
免疫原：

Human C21orf66
免疫原種屬：

Homo sapiens (Human)
抗體亞型：

IgG
純化方式：

Antigen Affinity purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
產品提供形式：

Liquid
應用范圍：

ELISA,WB
Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Adapter protein linking the transcription factors PAX3 and PAX7 to the histone methylation machinery and involved in myogenesis. Associates with a histone methyltransferase complex that specifically mediates dimethylation and trimethylation of 'Lys-4' of histone H3. Mediates the recruitment of that complex to the transcription factors PAX3 and PAX7 on chromatin to regulate the expression of genes involved in muscle progenitor cells proliferation including ID3 and CDC20.
基因功能參考文獻：
1. A homozygous potentially pathogenic variant in the PAXBP1 gene in a large family with global developmental delay and myopathic hypotonia has been reported. PMID: 28542722
2. The GCFC1/C21orf66 distal promoter contains an inhibitory cis-regulatory element that is responsive to Trichostatin A (TSA) treatment according to promoter reporter assays in HEK 293 cells. PMID: 20494980
亞細胞定位：

Nucleus.
蛋白家族：

GCF family
組織特異性：

Ubiquitous.
數據庫鏈接：

HGNC: 13579

OMIM: 617621

KEGG: hsa:94104

STRING: 9606.ENSP00000328992

UniGene: Hs.644004

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