PAFAH2 Antibody, Biotin conjugated
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中文名稱：PAFAH2兔多克隆抗體, Biotin偶聯
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貨號：CSB-PA857448LD01HU
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規格：￥880
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其他：
產品詳情
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產品名稱：Rabbit anti-Homo sapiens (Human) PAFAH2 Polyclonal antibody
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Uniprot No.：
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基因名：PAFAH2
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別名：PAFAH2Platelet-activating factor acetylhydrolase 2 antibody; cytoplasmic antibody; EC 3.1.1.47 antibody; Serine-dependent phospholipase A2 antibody; SD-PLA2 antibody; hSD-PLA2 antibody
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宿主：Rabbit
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反應種屬：Human
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免疫原：Recombinant Human Platelet-activating factor acetylhydrolase 2, cytoplasmic protein (1-206AA)
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免疫原種屬：Homo sapiens (Human)
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標記方式：Biotin
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：>95%, Protein G purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 -
產品提供形式：Liquid
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應用范圍：ELISA
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Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Catalyzes the hydrolyze of the acetyl group at the sn-2 position of platelet-activating factor (PAF) and its analogs, leading to their inactivation. Hydrolyzes propionyl and butyroyl moieties approximately half as effectively as PAF. Also catalyzes transacetylation of the acetyl group from platelet-activating factor (PAF) to lysoplasmalogen and to sphingosine, producing plasmalogen analogs of PAF and N-acetylsphingosine (C2-ceramide) respectively. Has a marked selectivity for phospholipids with short acyl chains at the sn-2 position.
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基因功能參考文獻：
- Data show that the activity of plasma platelet activating factor acetylhydrolase (PAF-AH) increases in parallel with diabetic retinopathy (DR) severity. PMID: 26791393
- The oligomeric state of PAFAH-II drives functional protein trafficking. PAFAH-II localization to the membrane is critical for substrate acquisition and effective oxidative stress protection. PMID: 25707358
- presence of platelet-activating factor acetylhydrolase II in a restricted pattern in human skin; it is involved in protecting this organ against oxidative stress through the degradation of oxidatively modified bioactive phospholipids. PMID: 12406338
- Lp-PLA2 was higher in those with more extensive Coronary artery disease PMID: 17157859
- PAF-AH II exerts strong neuroprotective effects against ischemic injury: the neurological deficit scores, cerebral edema index, and relative infarction volume are all significantly lower in PAFAH2 transgenic mice than in wild-type mice. PMID: 17272759
- examines substrate specificity for intracellular and plasma PAF-AHs PMID: 11294621
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亞細胞定位：Cytoplasm. Membrane; Lipid-anchor. Endoplasmic reticulum membrane; Lipid-anchor.
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蛋白家族：Serine esterase family
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組織特異性：Broadly expressed in different tissues, but high in B- and T-lymphocytes. In brain, expression is restricted to amygdala and frontal cortex.
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數據庫鏈接：
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