OSR1 Antibody
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中文名稱：OSR1兔多克隆抗體
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貨號：CSB-PA017262GA01HU
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規格：￥3,900
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其他：
產品詳情
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Uniprot No.：
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基因名：OSR1
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別名：OSR1 antibody; ODD antibody; Protein odd-skipped-related 1 antibody
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宿主：Rabbit
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反應種屬：Human,Mouse,Rat
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免疫原：Human OSR1
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免疫原種屬：Homo sapiens (Human)
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抗體亞型：IgG
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純化方式：Antigen Affinity Purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
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產品提供形式：Liquid
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應用范圍：ELISA,WB
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Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Transcription factor that plays a role in the regulation of embryonic heart and urogenital development.
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基因功能參考文獻：
- Kir2.1 and Kir2.3, are activated by OSR1 through a motif variant, R-x-F-x-V/I. PMID: 29581290
- Odd-skipped related 1 (OSR1) downregulated the activity of the Wnt signaling pathway by suppressing the expression of sex-determining region Y-box 9 (SOX9) and beta-catenin. PMID: 29660200
- OSR1 was downregulated in RCC cells by promoter methylation. OSR1 can function as a tumor suppressor via inhibition of invasion and proliferation in RCC cells, possibly via upregulating tumor suppressor genes and downregulating oncogenes. PMID: 28404905
- OSR1 was sequenced in 186 children with primary vesicoureteric reflux, and 17 have single nucleotide polymorphisms PMID: 28724605
- In summary, our study implicated a gene network involving Tbx5, Osr1 and Pcsk6 interaction in second heart field for atrial septation, providing a molecular framework for understanding the role of Tbx5 in congenital heart disease ontogeny. PMID: 26744331
- The findings of the present study showed, for the first time, the role of the OSR1 rs12329305 polymorphism in the development of congenital malformations in cases of stillborn/neonatal death. PMID: 25164089
- OSR1 acts as a functional tumour suppressor in gastric cancer PMID: 24931004
- OSR1 is expressed in human mesenchymal stem cells, the blastemal component of Wilms tumors and CD24+/CD133+ progenitor cells isolated from the mature kidney. PMID: 21821672
- first report on molecular cloning and characterization of human OSR1 PMID: 12119563
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亞細胞定位：Nucleus.
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蛋白家族：Odd C2H2-type zinc-finger protein family
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組織特異性：Expressed in adult colon, small intestine, prostate, testis, and fetal lung.
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數據庫鏈接：
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