NUSAP1 Antibody
-
中文名稱：NUSAP1兔多克隆抗體
-
貨號：CSB-PA016213GA01HU
-
規格：￥3,900
-
其他：
產品詳情
-
Uniprot No.：
-
基因名：NUSAP1
-
別名：2610201A12Rik antibody; AI481307 antibody; ANKT antibody; AW547774 antibody; BB165529 antibody; BM037 antibody; FLJ13421 antibody; LNP antibody; Nucleolar and spindle associated protein 1 antibody; Nucleolar and spindle-associated protein 1 antibody; Nucleolar protein ANKT antibody; NuSAP antibody; NUSAP_HUMAN antibody; nusap1 antibody; PRO0310p1 antibody; Q0310 antibody; RP23-22A15.4 antibody; SAPL antibody
-
宿主：Rabbit
-
反應種屬：Human,Mouse
-
免疫原：Human NUSAP1
-
免疫原種屬：Homo sapiens (Human)
-
抗體亞型：IgG
-
純化方式：Antigen Affinity Purified
-
濃度：It differs from different batches. Please contact us to confirm it.
-
保存緩沖液：PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
-
產品提供形式：Liquid
-
應用范圍：ELISA,WB,IHC,IF
-
Protocols：
-
儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
-
用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
-
功能：Microtubule-associated protein with the capacity to bundle and stabilize microtubules. May associate with chromosomes and promote the organization of mitotic spindle microtubules around them.
-
基因功能參考文獻：
- Study suggests that NUSAP1 might be involved in glioma progression and can serve as a prognosis biomarker for glioma patients. NUSAP1 silencing suppresses malignant phenotypes of glioma cells, which offer a theoretical foundation for further investigation of NUSAP1 as a possible target with advantages for glioma treatment. PMID: 29336114
- NUSAP1 is overexpressed in colon cancer and high expression of NUSAP1 acts as an independent predictive factor for poor prognosis in colon cancer PMID: 29853313
- Findings indicated that NUSAP1 played an important role in promoting aggressiveness in astrocytoma via activating the HH pathway. PMID: 28899410
- our work provides a better understanding of the function of NUSAP1 in aggressive prostate cancers, provides rationale for using NUSAP1 as a prognostic biomarker, and sets the stage for developing improved therapeutic strategies for prostate and other cancers. PMID: 28404898
- NUSAP1 contributes to accurate chromosome segregation by acting as a co-factor for RanBP2-RanGAP1-UBC9 during cell division. PMID: 28900032
- NuSAP governs chromosome oscillation via regulation of Kid, facilitating the Kid-generated polar ejection force. Depletion of NuSAP significantly suppresses the amplitude and velocity of chromosome oscillation. PMID: 26839278
- NUSAP1 may be a crucial biomarker for oral squamous cell carcinoma. down-regulated NUSAP1 expression suppresses tumor proliferation and also enhances anti-tumor effect of paclitaxel by activating apoptotic pathways. PMID: 26554377
- High levels of NuSAP1 expression were related to poor disease-free survival, particularly in triple-negative breast cancer. PMID: 26485712
- A novel association between BRCA1 and NUSAP1 is revealed and a mechanism whereby NUSAP1 is involved in carcinogenesis was elusidated. PMID: 24521615
- High NUSAP1 expression is associated with cervical cancer. PMID: 23405241
- NuSAP is a novel biomarker for prostate cancer recurrence after surgery and its overexpression appears to be driven in part by E2F1 activation PMID: 22349817
- Phosphorylation of NuSAP by Cdk1 is an important mechanism to regulate microtubule dynamics during cell cycle progression. PMID: 22101338
- Interphase NuSAP-chromatin interaction suggests additional functions for NuSAP, as recently identified for other nuclear spindle assembly factors with a role in gene expression or DNA damage response. PMID: 21782797
- NuSAP1 is recognized as an immunogenic antigen in 65% of patients with AML following allogeneic HCT and suggests a tumor antigen role. PMID: 20053754
顯示更多
收起更多
-
亞細胞定位：Cytoplasm. Nucleus, nucleolus. Cytoplasm, cytoskeleton, spindle. Chromosome.
-
蛋白家族：NUSAP family
-
數據庫鏈接：
Most popular with customers
-
-
YWHAB Recombinant Monoclonal Antibody
Applications: ELISA, WB, IHC, IF, FC
Species Reactivity: Human, Mouse, Rat
-
-
-
-
-
-
