NUP93 Antibody, FITC conjugated
產(chǎn)品詳情
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產(chǎn)品名稱：
Rabbit anti-Homo sapiens (Human) NUP93 Polyclonal antibody
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Uniprot No.：
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基因名：
NUP93
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別名：
NUP93 antibody; KIAA0095Nuclear pore complex protein Nup93 antibody; 93 kDa nucleoporin antibody; Nucleoporin Nup93 antibody
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宿主：
Rabbit
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反應(yīng)種屬：
Human
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免疫原：
Recombinant Human Nuclear pore complex protein Nup93 protein (14-180AA)
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免疫原種屬：
Homo sapiens (Human)
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標(biāo)記方式：
FITC
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克隆類型：
Polyclonal
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抗體亞型：
IgG
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純化方式：
>95%, Protein G purified
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濃度：
It differs from different batches. Please contact us to confirm it.
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保存緩沖液：
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
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產(chǎn)品提供形式：
Liquid
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儲(chǔ)存條件：
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：
For Research Use Only. Not for use in diagnostic or therapeutic procedures.
靶點(diǎn)詳情
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功能：
Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance. May anchor nucleoporins, but not NUP153 and TPR, to the NPC. During renal development, regulates podocyte migration and proliferation through SMAD4 signaling.
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基因功能參考文獻(xiàn)：
- we show that knockdown of Nup188 or its binding partner Nup93 leads to a loss of cilia during embryonic development while leaving NPC function largely intact. Many data, including the localization of endogenous Nup188/93 at cilia bases, support their direct role at cilia. Super-resolution imaging of Nup188 shows two barrel-like structures PMID: 27593162
- NUP93 and exportin 5 interact with the signaling protein SMAD4 and that NUP93 mutations abrogated interaction with SMAD4 PMID: 26878725
- Caspases target only Nup93 and Nup96 within the core structure of the nuclear pore complex PMID: 16286466
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相關(guān)疾病：
Nephrotic syndrome 12 (NPHS12)
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亞細(xì)胞定位：
Nucleus membrane; Peripheral membrane protein. Nucleus, nuclear pore complex. Nucleus envelope.
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蛋白家族：
Nucleoporin interacting component (NIC) family
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數(shù)據(jù)庫(kù)鏈接：
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