NME7 Antibody, Biotin conjugated

說明書

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) NME7 Polyclonal antibody
Uniprot No.：

Q9Y5B8
基因名：

NME7
別名：

MN23H7 antibody; NDK 7 antibody; NDK7_HUMAN antibody; NDP kinase 7 antibody; nm23 H7 antibody; nm23-H7 antibody; NME/NM23 family member 7 antibody; Nme7 antibody; Non metastatic cells 7 protein expressed in (nucleoside diphosphate kinase) antibody; Nucleoside diphosphate kinase 7 antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Nucleoside diphosphate kinase 7 protein (1-150AA)
免疫原種屬：

Homo sapiens (Human)
標記方式：

Biotin
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA
Protocols：

ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
基因功能參考文獻：
1. Study provides evidence that the deleterious mutation in NME7, which results in deletion of amino acids necessary for its interaction with Gamma-tubulin ring complex associated with impaired left-right asymmetry manifested by Situs Inversus Totalis. PMID: 27060491
2. RNA-seq analysis shows vast differences between the parent FGF2 grown, primed state cells, and NME7AB converted cells, but similarities to altered gene expression patterns reported by others generating naive-like stem cells via the use of biochemical inhibitors PMID: 26749426
3. NME7 functions in the gamma-tubulin ring complex in a kinase-dependent manner to facilitate microtubule nucleation. PMID: 24807905
4. Compared with wild-type betagamma nucleoside diphosphate kinase overexpression of Gbeta nucleoside diphosphate kinase suppressed basal cAMP formation up to 55%. PMID: 17363702
蛋白家族：

NDK family
數據庫鏈接：

HGNC: 20461

OMIM: 613465

KEGG: hsa:29922

STRING: 9606.ENSP00000356785

UniGene: Hs.706952

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