NFIA Antibody
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中文名稱：NFIA兔多克隆抗體
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貨號：CSB-PA015754GA01HU
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規格：￥3,900
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其他：
產品詳情
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Uniprot No.：
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基因名：NFIA
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別名：1110047K16Rik antibody; 9430022M17Rik antibody; CCAAT Box Binding Transcription Factor antibody; CCAAT-box-binding transcription factor antibody; CTF antibody; FLJ39164 antibody; NF I/A antibody; NF-I/A antibody; NF1-A antibody; NFI A antibody; NFI L antibody; NFI-A antibody; NFIA antibody; NFIA_HUMAN antibody; Nuclear factor 1 A type antibody; Nuclear factor 1 A-type antibody; Nuclear factor 1/A antibody; Nuclear factor I/A antibody; TGGCA binding protein antibody; TGGCA-binding protein antibody
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宿主：Rabbit
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反應種屬：Human,Mouse,Rat
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免疫原：Human NFIA
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免疫原種屬：Homo sapiens (Human)
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抗體亞型：IgG
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純化方式：Antigen Affinity Purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
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產品提供形式：Liquid
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應用范圍：ELISA,WB,IHC
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Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication.
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基因功能參考文獻：
- The consistent overlap in clinical presentation provides further evidence of the critical role of NFIA haploinsufficiency in the development of the 1p32-p31 microdeletion syndrome phenotype. PMID: 28941020
- Data define a previously unknown nuclear factor I-A-nuclear factor-kappaB feed-forward regulation that may contribute to glioblastoma cell survival. PMID: 27994064
- Studies indicate the role of nuclear factor one (NFIs) as epigenetic regulators in cancer. PMID: 28076901
- Altogether, these results demonstrated that miR-370 suppressed hepatitis B virus gene expression and replication through repressing NFIA expression, which stimulates hepatitis B virus replication via direct regulation on hepatitis B virus Enhancer I activities. PMID: 27664977
- We verified that NFIA binds to the IGFBP2 promoter and transcriptionally enhances IGFBP2 expression levels. We identified that NFIA-mediated IGFBP2 signaling pathways are involved in miR-302b-induced glioma cell death. PMID: 28323865
- miR-191 was upregulated in patients with middle- and late-stage NSCLC, and in NSCLC cell lines, under mild hypoxic conditions. miR-191 promoted the proliferation and migration of NSCLC under chronic hypoxic conditions, and this promotion may be associated with its targeting of NFIA. PMID: 28075452
- Dihydrocapsaicin can significantly decrease proinflammatory cytokines through enhancing NFIA and inhibiting NF-kappaB expression PMID: 27267730
- These results demonstrated that RP5833A20.1 inhibited tumor cell proliferation, induced apoptosis and inhibited cellcycle progression by suppressing the expression of NFIA in U251 cells. PMID: 27779670
- NFI-A is involved in the miR-21-induced expression of IL-10 in B cells in nasopharyngeal carcinoma; Il-10 is capable of suppressing CD8+ T-cell activities. PMID: 25544502
- microRNA-136 targeted and degraded NFIA, which induced the release of microRNA-223, promoting CD11b expression. Direct base pairing occurs between miR-136 and the 3' UTR of NFIA mRNA. PMID: 26329426
- this family also carried a microdeletion affecting solely the NFIA gene, this study substantiates the importance of this gene in craniofacial development. PMID: 25714559
- TGF-beta-mediated suppression of ANT2 through NF1/Smad4 complexes contributes to oxidative stress and DNA damage during induction of cellular senescence. PMID: 25220407
- a strong candidate gene for asthma and allergic rhinitis PMID: 24560411
- RP5-833A20.1/miR-382-5p/NFIA pathway was essential to the regulation of cholesterol homeostasis and inflammatory reactions. PMID: 25265644
- This report presents the first case of an intragenic deletion within the NFIA gene that is still consistent with classic clinical phenotypes present in previously reported cases of chromosome 1p31.3 related deletion. PMID: 24462883
- High nuclear factor IA expression is associated with glioblastomas. PMID: 24305710
- These studies represent the first characterization of miR-223/NFIA axis function in glioma PMID: 23946414
- These data suggest that genetic variants in the NF1A gene region may predispose to seasonal patterned of mania in bipolar disorder. PMID: 22925353
- NFIA expression in white matter lesions of human newborns with neonatal HIE, as well active MS lesions in adults, revealed that it is similarly expressed in oligodendrocyte progenitors and not oligodendrocytes. PMID: 22807310
- Role in the expression mechanism of hNaPi-IIb gene transcription. PMID: 15458926
- nuclear factor I has a role in the intrinsic control of cerebellar granule neuron gene expression PMID: 15466411
- Distribution of nuclear factor I binding sites correlate with Z-DNA forming regions in human chromosome 22. PMID: 15598822
- Data show that human granulocytic differentiation is controlled by a regulatory circuitry involving miR-223 and two transcriptional factors, NFI-A and C/EBPalpha. PMID: 16325577
- The NF1-A transcription factor plays an important role in the transcriptional activation of the TR2 orphan receptor gene expression via a promoter activating cis-element. PMID: 17010934
- The mouse Nfia mutant phenotype and the common features among five human cases indicate that NFIA haploinsufficiency contributes to a novel human central nervous system malformation syndrome that can also include ureteral and renal defects. PMID: 17530927
- NFI family of transcription factors plays a key role in the regulation of both the B-FABP and GFAP genes in malignant glioma cells. PMID: 19540848
- in early hematopoiesis, the NFI-A expression level acts as a novel factor channeling HPCs into either the E or G lineage PMID: 19542302
- Disruption of the Nfia gene in the mouse causes perinatal lethality, agenesis of the corpus callosum and hydrocephalus. PMID: 10518556
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相關疾?。?/div>Brain malformations with or without urinary tract defects (BRMUTD)亞細胞定位：Nucleus.蛋白家族：CTF/NF-I family數據庫鏈接：
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