MYRIP Antibody, HRP conjugated
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中文名稱：MYRIP兔多克隆抗體, HRP偶聯
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貨號：CSB-PA839876LB01HU
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規格：￥880
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其他：
產品詳情
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產品名稱：Rabbit anti-Homo sapiens (Human) MYRIP Polyclonal antibody
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Uniprot No.：
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基因名：MYRIP
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別名：DKFZp586F1018 antibody; Exophilin 8 antibody; Exophilin antibody; Exophilin-8 antibody; Exophilin8 antibody; FLJ44025 antibody; MGC130034 antibody; MGC130035 antibody; Myosin VIIA and Rab interacting protein antibody; Myosin-VIIa- and Rab-interacting protein antibody; Myrip antibody; MYRIP_HUMAN antibody; Rab effector MyRIP antibody; SLAC 2C antibody; SLAC2 C antibody; SlaC2-c antibody; SLAC2C antibody; Slp homolog lacking C2 domains c antibody; Slp homologue lacking C2 domains antibody; Slp homologue lacking C2 domains c antibody; Synaptotagmin like protein homologue lacking C2 domains c antibody; synaptotagmin-like protein lacking C2 domains C antibody
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宿主：Rabbit
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反應種屬：Human
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免疫原：Recombinant Human Rab effector MyRIP protein (387-689AA)
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免疫原種屬：Homo sapiens (Human)
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標記方式：HRP
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：>95%, Protein G purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 -
產品提供形式：Liquid
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應用范圍：ELISA
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Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Rab effector protein involved in melanosome transport. Serves as link between melanosome-bound RAB27A and the motor proteins MYO5A and MYO7A. May link RAB27A-containing vesicles to actin filaments. Functions as a protein kinase A-anchoring protein (AKAP). May act as a scaffolding protein that links PKA to components of the exocytosis machinery, thus facilitating exocytosis, including insulin release.
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基因功能參考文獻：
- The role of MyRIP in Ca(2+)-driven exocytosis requires both MyoVa- and actin-binding potential. PMID: 26675235
- Myrip couples the retention of secretory granules in the cell cortex, their transport to the plasma membrane, and their attachment to the plasma membrane, thus promoting secretion. PMID: 22396429
- A Rab27a/MyRIP/myosin Va complex is involved in linking von-Willebrand factor (Vwf) to the peripheral actin cytoskeleton of endothelial cells to allow full maturation and prevent premature secretion of vWF. PMID: 21740491
- A new potentially protective effect was identified at rs2679798 in MYRIP. PMID: 20861866
- a molecular complex composed of Rab27A, MyRIP and myosin VIIa bridges retinal melanosomes to the actin cytoskeleton and thereby mediates the local trafficking of these organelles PMID: 11964381
- Slac2c/MyRIP is part of a complex mediating the interaction of secretory granules with cortical actin cytoskeleton PMID: 14517322
- During primate spermiogenesis, dynein, myosin Va, MyRIP and Rab27b that compose microtubule-based and actin-based vesicle transport systems are actually present in the manchette and might possibly be involved in intramanchette transport. PMID: 18478159
- Rab27a and MyRIP regulate the amount and multimeric state of VWF released from endothelial cells. PMID: 19270261
- Slac2-c/MyRIP contains an N-terminal Slp homology domain (SHD) and functions as a linker protein that interacts with myosin Rab27A/B, VIIa/Va, and actin. PMID: 12221080
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亞細胞定位：Cytoplasm. Cytoplasm, perinuclear region. Cytoplasmic vesicle, secretory vesicle.
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組織特異性：Detected in brain, skin, heart, adrenal medulla, pancreas, intestine, liver, kidney, muscle and testis.
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數據庫鏈接：
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