MED13 Antibody

說明書

中文名稱：

MED13兔多克隆抗體
貨號：

CSB-PA149000
規格：

￥1100
圖片：
Gel: 6%SDS-PAGE, Lysate: 40 μg, Lane: K562 cells, Primary antibody: CSB-PA149000(MED13 Antibody) at dilution 1/300, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 minutes
其他：

產品詳情

Uniprot No.：

Q9UHV7
基因名：

MED13
別名：

MED13 antibody; ARC250 antibody; KIAA0593 antibody; THRAP1 antibody; TRAP240 antibody; Mediator of RNA polymerase II transcription subunit 13 antibody; Activator-recruited cofactor 250 kDa component antibody; ARC250 antibody; Mediator complex subunit 13 antibody; Thyroid hormone receptor-associated protein 1 antibody; Thyroid hormone receptor-associated protein complex 240 kDa component antibody; Trap240 antibody; Vitamin D3 receptor-interacting protein complex component DRIP250 antibody; DRIP250 antibody
宿主：

Rabbit
反應種屬：

Human,Mouse
免疫原：

Synthetic peptide of Human MED13
免疫原種屬：

Homo sapiens (Human)
標記方式：

Non-conjugated
抗體亞型：

IgG
純化方式：

Antigen affinity purification
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
產品提供形式：

Liquid
應用范圍：

ELISA,WB

推薦稀釋比：

Application	Recommended Dilution
ELISA	1:2000-1:5000
WB	1:500-1:2000

Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
基因功能參考文獻：
1. Each of HSPA4 and MED13 mutations were detected in GC. PMID: 27129500
2. Cardiac overexpression of MED13 in transgenic mice confers a lean phenotype that is associated with increased lipid uptake, beta-oxidation and mitochondrial content in white adipose tissue and liver PMID: 25422356
3. Med12 and Med13 are critical for human CDK8 subcomplex -dependent repression, whereas CDK8 kinase activity is not PMID: 19240132
亞細胞定位：

Nucleus.
蛋白家族：

Mediator complex subunit 13 family
組織特異性：

Ubiquitous.
數據庫鏈接：

HGNC: 22474

OMIM: 603808

KEGG: hsa:9969

STRING: 9606.ENSP00000380888

UniGene: Hs.282678

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