MAST1 Antibody

文獻引用 (2) 說明書

中文名稱：

MAST1兔多克隆抗體
貨號：

CSB-PA897529LA01HU
規格：

￥440
圖片：
Immunohistochemistry of paraffin-embedded human prostate cancer using CSB-PA897529LA01HU at dilution of 1:100

Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA897529LA01HU at dilution of 1:100

Immunofluorescent analysis of Hela cells using CSB-PA897529LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
其他：

產品詳情
產品評價
引用文獻
相關產品
靶點詳情

產品詳情

產品描述：

MAST1 polyclonal antibody CSB-PA897529LA01HU was produced in the rabbit immunized by using the Recombinant Human Microtubule-associated serine/threonine-protein kinase 1 protein (687-879AA) as the immunogen. The target protein MAST1 is essential for correct brain development, and appears to link the dystrophin/utrophin network with microtubule filaments via the syntrophins. Diseases associated with MAST1 include Mega-Corpus-Callosum Syndrome With Cerebellar Hypoplasia And Cortical Malformations and Cerebellar Hypoplasia.
This Rabbit anti-Homo sapiens (Human) MAST1 Polyclonal antibody was tested in the ELISA, IHC and IF applications. The non-conjugated IgG got purified by protein G and reached up to 95% in purity. It only reacts with the MAST1 proteins of human-origin and may be used to detect the endogenous levels of MAST1 protein.
產品名稱：

Rabbit anti-Homo sapiens (Human) MAST1 Polyclonal antibody
Uniprot No.：

Q9Y2H9
基因名：

MAST1
別名：

9430008B02Rik antibody; KIAA0973 antibody; MAST 1 antibody; MAST1 antibody; MAST1_HUMAN antibody; Microtubule associated serine/threonine kinase 1 antibody; Microtubule associated serine/threonine protein kinase 1 antibody; Microtubule-associated serine/threonine-protein kinase 1 antibody; SAST 124 antibody; SAST 170 antibody; SAST antibody; SAST170 antibody; Syntrophin associated serine/threonine kinase antibody; Syntrophin associated serine/threonine protein kinase antibody; Syntrophin-associated serine/threonine-protein kinase antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Microtubule-associated serine/threonine-protein kinase 1 protein (687-879AA)
免疫原種屬：

Homo sapiens (Human)

標記方式：

Non-conjugated

本頁面中的產品，MAST1 Antibody (CSB-PA897529LA01HU)，的標記方式是Non-conjugated。對于MAST1 Antibody，我們還提供其他標記。見下表：

標記方式	貨號	產品名稱	應用
HRP	CSB-PA897529LB01HU	MAST1 Antibody, HRP conjugated	ELISA
FITC	CSB-PA897529LC01HU	MAST1 Antibody, FITC conjugated
Biotin	CSB-PA897529LD01HU	MAST1 Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA, IHC, IF

推薦稀釋比：

Application	Recommended Dilution
IHC	1:20-1:200
IF	1:50-1:200

Protocols：

ELISA Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

引用文獻

USP28 promotes tumorigenesis and cisplatin resistance by deubiquitinating MAST1 protein in cancer cells JK Karapurkar,Cellular and molecular life sciences,2024
CRISPR/Cas9-based genome-wide screening for deubiquitinase subfamily identifies USP1 regulating MAST1-driven cisplatin-resistance in cancer cells A Tyagi,Theranostics,2022

產品評價

靶點詳情

功能：

Microtubule-associated protein essential for correct brain development. Appears to link the dystrophin/utrophin network with microtubule filaments via the syntrophins. Phosphorylation of DMD or UTRN may modulate their affinities for associated proteins.
基因功能參考文獻：
1. Overexpression of MAST1 or MAST2 gene fusions has a proliferative effect both in vitro and in vivo in breast cancer cell lines. PMID: 22101766
2. Discusses cloning of Sast, the mouse ortholog of human MAST1. PMID: 10404183
3. Discusses cloning of Sast124, the rat ortholog of MAST1. PMID: 12614677
亞細胞定位：

Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton. Cell projection, axon. Cell projection, dendrite.
蛋白家族：

Protein kinase superfamily, AGC Ser/Thr protein kinase family
組織特異性：

Expressed in fetal brain.
數據庫鏈接：

HGNC: 19034

OMIM: 612256

KEGG: hsa:22983

STRING: 9606.ENSP00000251472

UniGene: Hs.227489

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