MAGEA10 Antibody

說明書

產品詳情

Uniprot No.：

P43363
基因名：

MAGEA10
別名：

MAGEA10 antibody; MAGE10Melanoma-associated antigen 10 antibody; Cancer/testis antigen 1.10 antibody; CT1.10 antibody; MAGE-10 antigen antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Human MAGEA10
免疫原種屬：

Homo sapiens (Human)
抗體亞型：

IgG
純化方式：

Antigen Affinity purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
產品提供形式：

Liquid
應用范圍：

ELISA,WB
Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Not known, though may play a role in embryonal development and tumor transformation or aspects of tumor progression.
基因功能參考文獻：
1. By using Molecular-Docking, 3 MAGEA10 peptides were found binding to the groove position of HLA-A( *)0210 same as MAGEA4 peptide co-crystallized with HLA-A( *)0210, which indicates they could be promising for HLA-A( *)0201 presentation in immunotherapy. PMID: 26058806
2. We clearly showed that MAGE-A10 is frequently expressed in the group of triple-negative breast cancer patients PMID: 22116775
3. High MAGE-A10 is associated with lung, skin and urothelial malignancies. PMID: 21710496
4. This is the first report of these MAGE-A10 alternative splice sequences, and characterization of MAGE-A expression PMID: 15355897
亞細胞定位：

Nucleus.
組織特異性：

Expressed in many tumors of several types, such as melanoma, head and neck squamous cell carcinoma, lung carcinoma and breast carcinoma, but not in normal tissues except for spermatogonia, spermatocytes and placenta.
數據庫鏈接：

HGNC: 6797

OMIM: 300343

KEGG: hsa:4109

STRING: 9606.ENSP00000244096

UniGene: Hs.18048

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