LSM4 Antibody
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中文名稱：LSM4兔多克隆抗體
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貨號：CSB-PA013207GA01HU
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規(guī)格：￥3,900
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其他：
產(chǎn)品詳情
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Uniprot No.：
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基因名：LSM4
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別名：LSM4U6 snRNA-associated Sm-like protein LSm4 antibody; Glycine-rich protein antibody; GRP antibody
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宿主：Rabbit
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反應(yīng)種屬：Human,Mouse,Rat
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免疫原：Human LSM4
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免疫原種屬：Homo sapiens (Human)
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抗體亞型：IgG
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純化方式：Antigen Affinity Purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
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產(chǎn)品提供形式：Liquid
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應(yīng)用范圍：ELISA,WB,IHC
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Protocols：
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儲(chǔ)存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產(chǎn)品評價(jià)
相關(guān)產(chǎn)品
靶點(diǎn)詳情
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功能：Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.
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基因功能參考文獻(xiàn)：
- Results show that the RGG domain of human Lsm4 stimulates processing bodies formation. Also, a novel interaction of the Lsm4 RGG domain with HAT1 and RBBP7 was discovered, leading to the possibility of a posttranslational modifications network involved in mRNP regulation. PMID: 27247266
- C-terminal extension of Lsm4 interacts directly with the histone mRNP, contacting both SLBP and 3'hExo. PMID: 24255165
- Data show that ICln159, a truncated ICln mutant, belongs to the pleckstrin homology (PH) domain family of proteins and interacts with LSm4, a protein involved in splicing and mRNA degradation. PMID: 15905169
- Gene induces transformed phenotype when overexpressed in a cancer breast cell line. PMID: 17178857
- LSm4 not only acts in RNA processing, but also as a co-factor in cell volume regulation. PMID: 19088440
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亞細(xì)胞定位：Nucleus.
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蛋白家族：SnRNP Sm proteins family
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數(shù)據(jù)庫鏈接：
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