LRRFIP2 Antibody, Biotin conjugated
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中文名稱：LRRFIP2兔多克隆抗體, Biotin偶聯
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貨號：CSB-PA896921LD01HU
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規格：￥880
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其他：
產品詳情
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產品名稱：Rabbit anti-Homo sapiens (Human) LRRFIP2 Polyclonal antibody
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Uniprot No.：
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基因名：LRRFIP2
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別名：5133400F20Rik antibody; AI850587 antibody; DKFZp434H2035 antibody; FLJ20248 antibody; FLJ22683 antibody; FLJ58304 antibody; HUFI 2 antibody; Leucine rich repeat (in FLII) interacting protein 2 antibody; Leucine rich repeat flightless interacting protein 2 antibody; Leucine-rich repeat flightless-interacting protein 2 antibody; LRR FLII interacting protein 2 antibody; LRR FLII-interacting protein 2 antibody; LRRF2_HUMAN antibody; Lrrfip2 antibody
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宿主：Rabbit
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反應種屬：Human
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免疫原：Recombinant Human Leucine-rich repeat flightless-interacting protein 2 protein (211-342AA)
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免疫原種屬：Homo sapiens (Human)
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標記方式：Biotin
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：>95%, Protein G purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 -
產品提供形式：Liquid
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應用范圍：ELISA
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Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：May function as activator of the canonical Wnt signaling pathway, in association with DVL3, upstream of CTNNB1/beta-catenin. Positively regulates Toll-like receptor (TLR) signaling in response to agonist probably by competing with the negative FLII regulator for MYD88-binding.
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基因功能參考文獻：
- Data show that the ability of Ca(2+) to accentuate the activity of NLRP3 inflammasome is abrogated in Flightless-I (FliI) and leucine-rich repeat FliI-interaction protein 2 (LRRFIP2)-knockdown macrophages. PMID: 27431477
- FATylation of LRRFIP2 occurs on two distinct sites, each being modified by a single FAT10 moiety. PMID: 23036196
- A novel exonic rearrangement affecting MLH1 and the contiguous LRRFIP2 is a founder mutation in Portuguese Lynch syndrome families PMID: 21785361
- Unambiguous characterization of site-specific phosphorylation of leucine-rich repeat Fli-I-interacting protein 2 (LRRFIP2) in Toll-like receptor 4 (TLR4)-mediated signaling. PMID: 21220426
- These data suggest that LRRFIP2 plays an important role in transducing Wnt signals. PMID: 15677333
- LRR-binding MyD88 interactor LRRFIP2 is a positive regulator of NF-kappa B activity and is also a positive regulator of cytokine production in lipopolysaccharide-stimulated macrophages, suggesting a functional role in TLR4-mediated inflammatory response. PMID: 19265123
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蛋白家族：LRRFIP family
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組織特異性：Widely expressed, with highest levels in heart and skeletal muscle.
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數據庫鏈接：
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