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中文名稱(chēng)：L兔多克隆抗體, HRP偶聯(lián)
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貨號(hào)：CSB-PA806333LB01VBE
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規(guī)格：￥880
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其他：
產(chǎn)品詳情
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產(chǎn)品名稱(chēng)：Rabbit anti-Vesicular stomatitis Indiana virus L Polyclonal antibody
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Uniprot No.：
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基因名：L
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別名：L antibody; RNA-directed RNA polymerase L antibody; Protein L antibody; Large structural protein antibody; Replicase antibody; Transcriptase) [Includes: RNA-directed RNA polymerase antibody; EC 2.7.7.48); mRNA antibody; guanine-N(7)-)-methyltransferase antibody; EC 2.1.1.56); GDP polyribonucleotidyltransferase antibody; EC 2.7.7.88); Cap-specific mRNA antibody; nucleoside-2'-O-)-methyltransferase 2 antibody; EC 2.1.1.296)] antibody
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宿主：Rabbit
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反應(yīng)種屬：Vesicular stomatitis Indiana virus
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免疫原：Recombinant Vesicular stomatitis Indiana virus RNA-directed RNA polymerase L protein (598-784AA)
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免疫原種屬：Vesicular stomatitis Indiana virus
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標(biāo)記方式：HRP
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克隆類(lèi)型：Polyclonal
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抗體亞型：IgG
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純化方式：>95%, Protein G purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 -
產(chǎn)品提供形式：Liquid
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應(yīng)用范圍：ELISA
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Protocols：
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儲(chǔ)存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產(chǎn)品評(píng)價(jià)
相關(guān)產(chǎn)品
靶點(diǎn)詳情
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功能：Responsible for RNA synthesis (replicase and transcriptase), cap addition, and cap methylation. Performs also the polyadenylation of subgenomic mRNAs by a stuttering mechanism at a slipery stop site present at the end of viral genes. The template is composed of the viral RNA tightly encapsidated by the nucleoprotein (N). The viral polymerase binds to the genomic RNA at the 3' leader promoter, thereby initiating either genome replication or mRNA transcription. In the transcription mode, the polymerase performs the sequential transcription of all mRNAs using a termination-reinitiation mechanism responding to gene start and gene end signals. Some polymerase disengage from the template at each gene junction, resulting in a decreasing abundance of transcripts from the 3' to the 5' end of the genome. The first gene is the most transcribed, and the last the least transcribed. The viral phosphoprotein helps the polymerase to engage the N-RNA template and acts as processivity factor. Polyribonucleotidyl transferase (PRNTase) adds the cap structure when the nascent RNA chain length has reached few nucleotides. Ribose 2'-O methylation of viral mRNA cap precedes and facilitates subsequent guanine-N-7 methylation, both activities being carried by the viral polymerase. In the replication mode, the polymerase replicates the whole viral genome without recognizing the gene end transcriptional signals. The ability of the polymerase to override the gene end signals as it is producing the antigenome is probably due to replicative RNA becoming encapsidated with nucleoprotein as it is synthesized.
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亞細(xì)胞定位：Virion. Host cytoplasm.
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蛋白家族：Rhabdoviridae protein L family
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