KRT17 Antibody, Biotin conjugated

^{Rare Species}

說明書

產品詳情

產品名稱：

Rabbit anti-Bovine KRT17 Polyclonal antibody
Uniprot No.：

A1L595
基因名：

KRT17
別名：

KRT17 antibody; Keratin antibody; type I cytoskeletal 17 antibody; Cytokeratin-17 antibody; CK-17 antibody; Keratin-17 antibody; K17 antibody
宿主：

Rabbit
反應種屬：

Bovine
免疫原：

Recombinant Bovine Keratin, type I cytoskeletal 17 protein (1-441AA)
免疫原種屬：

Bovine
標記方式：

Biotin
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA
Protocols：

ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Type I keratin involved in the formation and maintenance of various skin appendages, specifically in determining shape and orientation of hair. Required for the correct growth of hair follicles, in particular for the persistence of the anagen (growth) state. Modulates the function of TNF-alpha in the specific context of hair cycling. Regulates protein synthesis and epithelial cell growth through binding to the adapter protein SFN and by stimulating Akt/mTOR pathway. Involved in tissue repair. May be a marker of basal cell differentiation in complex epithelia and therefore indicative of a certain type of epithelial 'stem cells'. Acts as a promoter of epithelial proliferation by acting a regulator of immune response in skin: promotes Th1/Th17-dominated immune environment contributing to the development of basaloid skin tumors. May act as an autoantigen in the immunopathogenesis of psoriasis, with certain peptide regions being a major target for autoreactive T-cells and hence causing their proliferation.
亞細胞定位：

Cytoplasm.
蛋白家族：

Intermediate filament family
數據庫鏈接：

KEGG: bta:281889

STRING: 9913.ENSBTAP00000008948

UniGene: Bt.91540

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