KIRREL2 Antibody, Biotin conjugated
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中文名稱：KIRREL2兔多克隆抗體, Biotin偶聯
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貨號：CSB-PA754407LD01HU
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規格：￥880
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其他：
產品詳情
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產品名稱：Rabbit anti-Homo sapiens (Human) KIRREL2 Polyclonal antibody
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Uniprot No.：
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基因名：KIRREL2
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別名：FILTRIN antibody; Kin of IRRE like 2 (Drosophila) antibody; Kin of IRRE-like protein 2 antibody; Kin of irregular chiasm like 2 antibody; Kin of irregular chiasm-like protein 2 antibody; KIRR2_HUMAN antibody; KIRREL2 antibody; NEPH3 antibody; Nephrin like 3 antibody; nephrin-like gene 1 antibody; Nephrin-like protein 3 antibody; NLG1 antibody
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宿主：Rabbit
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反應種屬：Human
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免疫原：Recombinant Human Kin of IRRE-like protein 2 protein (21-219AA)
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免疫原種屬：Homo sapiens (Human)
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標記方式：Biotin
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：>95%, Protein G purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 -
產品提供形式：Liquid
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應用范圍：ELISA
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Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：May regulate basal insulin secretion.
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基因功能參考文獻：
- SNP V353M confers high risk of renal failure in primary hematuric glomerulopathies and predisposition to microalbuminuria in the general population PMID: 28334007
- summarize the current knowledge of the functions of nephrin and Neph-family proteins and transcription factors and agents that control nephrin and Neph3 gene expression. PMID: 24219158
- Transcription of nephrin-Neph3 gene pair is synergistically activated by WT1 and NF-kappaB and silenced by DNA methylation. PMID: 21980157
- Identification of Filtrin as a member of nephrin-like proteins. PMID: 12504092
- KIRREL2 protein is a beta-cell-expressed Ig domain protein and may be involved in pancreas development or beta cell function PMID: 12837264
- Filtrin can act as autoantigen, and autoantibodies against these can be detected in patients with type 1 diabetes. PMID: 16741999
- NF-kappaB and Sp1 response elements are essential for the basal transcriptional activity of the Neph3 promoter. PMID: 19703278
- Filtrin is a novel protein with substantial homology to nephrin. It is a transmembrane protein of the immunoglobulin superfamily (apparent molecular weight 107 kDa) and most prominently expressed in the pancreas, lymph nodes as well as kidney glomerulus. PMID: 12504092
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亞細胞定位：Cell membrane; Single-pass type I membrane protein.
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蛋白家族：Immunoglobulin superfamily
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組織特異性：Highly expressed in beta-cells of the pancreatic islets.
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數據庫鏈接：
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