KIF6 Antibody
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中文名稱：KIF6兔多克隆抗體
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貨號：CSB-PA012344GA01HU
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規格：￥3,900
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其他：
產品詳情
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Uniprot No.：
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基因名：
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別名：KIF6 antibody; C6orf102Kinesin-like protein KIF6 antibody
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宿主：Rabbit
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反應種屬：Human,Mouse,Rat
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免疫原：Human KIF6
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免疫原種屬：Homo sapiens (Human)
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抗體亞型：IgG
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純化方式：Antigen Affinity purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
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產品提供形式：Liquid
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應用范圍：ELISA,WB,IHC
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Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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基因功能參考文獻：
- The result suggests that KIF6 rs20455 polymorphism may not be associated with coronary heart disease susceptibility. (Meta-analysis) PMID: 29304815
- his represents the first study implicating KIF6 variants with obesity in men, and point to the possible involvement of this genetic locus in the known gender-related differences in coronary artery disease. PMID: 29295555
- The Trp719Arg polymorphism of the KIF6 gene is an important risk factor for developing myocardial infarction and that allele 719Arg may have a protective association to present coronary heart disease in all populations [review; meta-analysis] PMID: 28096762
- The absence of Trp719Arg polymorphism association with coronary artery disease (CAD) and CAD in stratified myocardial infarction cases indicates that the polymorphism is not associated with an increased risk among CAD patients from the Eastern Province of Saudi Arabia PMID: 26997531
- KIF6 polymorphism rs20455 had a significant association with Coronary Heart Disease; statin therapy was more effective in rs20455 carriers than non-carriers PMID: 26443250
- KIF6 719Arg allele may increase the risk of T2DM and T2DM + CHD only in Han Chinese men by modulating lipid metabolism. PMID: 25629058
- Our case-control study suggests that Trp719Arg of KIF6 gene is associated with coronary heart disease in female Han Chinese through a post hoc analysis. PMID: 23236363
- KIF6 719Arg allele was not an independent risk factor for angiographic coronary artery disease(CAD)susceptibility in northern China Han populations; it was associated with a significantly higher TG level, which may indicate increased myocardial infarction risk in angiographic CAD patients PMID: 23001387
- These data suggest that decreased availability of functional KLF6 contributes to clinical prostate cancer progression. PMID: 22819534
- In a meta-analysis involving 144,931 participants, the KIF6 719Arg allele was not associated with the relative risk of cardiovascular disease PMID: 22216121
- Assessment of KIF6 genotype is not useful in predicting low density lipoprotein cholesterol lowering response to pravastatin, and heart disease risk reduction in the elderly. PMID: 22192511
- Carriers of the KIF6 719Arg allele were not at increased risk of CAD/non-fatal MI in a case-control study of Indians (Indo-Europeans) living in Western India. PMID: 21810021
- In patients with type 2 diabetes mellitus on hemodialysis, KIF6 Trp719Arg genotypes were not associated with adverse cardiovascular outcomes during follow-up or with the efficacy of atorvastatin therapy. PMID: 21871624
- Discovered influence of polymorphic marker Trp719Arg of KIF6 gene on individual response to therapy with 10 mg/day of atorvastatin. PMID: 21943003
- A combination of KIF6 719Arg carrier status and C-reactive protein levels modestly improves the prediction of risk of myocardial infarction among white men. PMID: 21406102
- Use of KIF6 genotyping to guide statin therapy is not warranted in this heart protection trial, since no impact is found on KIF6 genotype, vascular risk or statin response. PMID: 21458191
- Carriers of the KIF6 719Arg allele were not at increased risk of non-fatal myocardial infarction. PMID: 20927332
- three highly linked SNPs in the KIF6 region were identified that predict differential reduction of coronary events from statin therapy. PMID: 20886236
- review of data supporting association between KIF6 polymorphism and coronary heart disease (CHD) and association between KIF6 polymorphism and event reduction by statin therapy; discuss putative biologic role of this kinesin in the cause of CHD [review] PMID: 20854963
- the role of polymorphic marker Thr719Arg of kinesin 6 gene in development of ischemic heart disease, myocardial infarction, and in efficacy of therapy with statins (Review) PMID: 20659029
- Observational study and clinical trial of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator) PMID: 20886236
- Observational study of gene-disease association. (HuGE Navigator) PMID: 20927332
- Meta-analysis of gene-disease association. (HuGE Navigator) PMID: 20933357
- Elderly carriers of the KIF6 719Arg variant with prior vascular disease received significant benefit from pravastatin therapy. PMID: 20215968
- Kinesin-like protein-6 tryptophan719arginine polymorphism is not associated with risk of clinical coronary artery disease in this large replication study. PMID: 20933357
- a relationship between the presence of endothelial colony-forming cells and Arg/Arg genotype in KIF6 in patients with acute myocardial infarction. PMID: 20044086
- Observational study of gene-disease association. (HuGE Navigator) PMID: 20679960
- Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) PMID: 20379614
- Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator) PMID: 20403483
- pravastatin therapy significantly and substantially reduced primary end point events in carriers of the KIF6 719Arg allele but not in noncarriers. PMID: 20403483
- Observational study of gene-disease association. (HuGE Navigator) PMID: 19752551
- Clinical trial of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator) PMID: 20215968
- In both the CARE and the WOSCOPS trials, carriers of the KIF6 719Arg allele had an increased risk of coronary events, and pravastatin treatment substantially reduced that risk. PMID: 18222353
- Confirming and extending previous reports, carriers of the 719Arg allele of KIF6 have 34% higher risk of myocardial infarction and 24% higher risk of CHD compared with noncarriers among 25,283 women from the WHS. PMID: 18222354
- Carriers of 719Arg receive significantly greater benefit from intensive statin therapy than do noncarriers, a superior benefit that appears to be due to a mechanism distinct from lipid or CRP lowering. PMID: 18222355
- The KIF6 719Arg variant has been associated with an increased risk of coronary disease and an increased response to statin therapy. PMID: 18510970
- Observational study of gene-disease association. (HuGE Navigator) PMID: 19023099
- Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator) PMID: 18222353
- Observational study of gene-disease association. (HuGE Navigator) PMID: 18222354
- Clinical trial of gene-environment interaction and pharmacogenomic / toxicogenomic. (HuGE Navigator) PMID: 18222355
- Observational study of gene-disease association. (HuGE Navigator) PMID: 17975119
- Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator) PMID: 18073581
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亞細胞定位：Cytoplasm, cytoskeleton.
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蛋白家族：TRAFAC class myosin-kinesin ATPase superfamily, Kinesin family
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