JRK Antibody

Name: JRK Antibody
Brand: CUSABIO
SKU: CSB-PA525639NA01HU

說明書

產品詳情

標記方式：

Non-conjugated

本頁面中的產品，JRK Antibody (CSB-PA525639NA01HU)，的標記方式是Non-conjugated。對于JRK Antibody，我們還提供其他標記。見下表：

標記方式	貨號	產品名稱	應用
HRP	CSB-PA525639NB01HU	JRK Antibody, HRP conjugated	ELISA
FITC	CSB-PA525639NC01HU	JRK Antibody, FITC conjugated
Biotin	CSB-PA525639ND01HU	JRK Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA, WB

推薦稀釋比：

Application	Recommended Dilution
WB	1:500-1:5000

Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

May bind DNA.
基因功能參考文獻：
1. JRK expression was aberrantly elevated in 21% of colorectal cancers, 15% of breast and ovarian cancers and was associated with increased expression of beta-catenin target genes and increased cell proliferation PMID: 26455321
2. in the adult intestine, Ebd acts independently of Ewg in physiological Wnt signaling, but cooperates with Ewg to induce the hyperactivation of Wnt target gene expression following Apc1 loss. These findings have relevance for human tumorigenesis, as Jerky (JRK/JH8), the human Ebd homolog, promotes Wnt pathway hyperactivation and is overexpressed in colorectal, breast, and ovarian cancers PMID: 28708826
亞細胞定位：

Nucleus.
蛋白家族：

Tigger transposable element derived protein family
組織特異性：

Expressed ubiquitously.
數據庫鏈接：

HGNC: 6199

OMIM: 603210

KEGG: hsa:8629

UniGene: Hs.535903

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