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中文名稱：IL1B兔多克隆抗體
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貨號：CSB-PA011614HA01SH
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規格：￥440
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圖片：
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Western blot
All lanes: IL1B antibody at 2µg/ml
Lane 1: Recombinant Interleukin-1 beta protein 0.05µg
Lane 2: Recombinant Interleukin-1 beta protein 0.5µg
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 31 kDa
Observed band size: 31 kDa
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其他：
產品詳情
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產品名稱：Rabbit anti-Sheep IL1B Polyclonal antibody
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Uniprot No.：
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基因名：
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別名：IL1BInterleukin-1 beta antibody; IL-1 beta antibody
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宿主：Rabbit
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反應種屬：Sheep
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免疫原：Recombinant Sheep Interleukin-1 beta protein (114-266AA)
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免疫原種屬：Sheep
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標記方式：Non-conjugated
本頁面中的產品，IL1B Antibody (CSB-PA011614HA01SH)，的標記方式是Non-conjugated。對于IL1B Antibody，我們還提供其他標記。見下表：
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：>95%, Protein G purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 -
產品提供形式：Liquid
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應用范圍：ELISA, WB
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推薦稀釋比：
Application Recommended Dilution WB 1:1000-1:5000 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells. Plays a role in angiogenesis by inducing VEGF production synergistically with TNF and IL6.
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基因功能參考文獻：
- Intravenous injection of SB203580 successfully inhibited synthesis of IL-1beta and reduced the production of IL-6 in the hypothalamus. PMID: 24995301
- Interleukin-1beta was increased only on the injured side of multifidus in disc disease. PMID: 24718080
- Inactivation of RhoA due to lack of prenylation leads to Rac1 activation and subsequent priming for IL-1beta secretion. PMID: 25107911
- RANTES-403 was significantly associated with the risk of developing diffuse-type gastric cancer in men and found a possible gene-gene interaction between RANTES and IL-1B polymorphisms in gastric cancer carcinogenesis. PMID: 24323564
- In vitro studies with IL-1-beta and TNF-alpha challenges, both proinflammatory cytokines resulted in elevated levels of CCL5 in conditioned media (p<0.01) PMID: 24468005
- These results showed that IL-1beta and IL-1 receptor types I and II were expressed in the ovine hypothalamus in response to lipopolysaccharide injection. PMID: 20345592
- These data are consistent with the effects of LPS on GH secretion originating through peripheral cytokine presentation to the pituitary, as well as a potential to act directly on selective populations of pituitary cells via CD14. PMID: 15899940
- plasma IL-1 beta, TNF-alpha and MCP-1 may potentially serve as markers to monitor prognosis of pregnancy toxaemia in ewes PMID: 17221363
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亞細胞定位：Cytoplasm, cytosol. Lysosome. Secreted, extracellular exosome. Secreted.
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蛋白家族：IL-1 family
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數據庫鏈接：
KEGG: oas:443539
UniGene: Oar.434
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