HMG20B Antibody
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中文名稱：HMG20B兔多克隆抗體
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貨號：CSB-PA788036
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規格：￥2024
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圖片：
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Western blot analysis of extracts from Jurkat cells, using HMG20B antibody.
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其他：
產品詳情
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產品名稱：Rabbit anti-Homo sapiens (Human) HMG20B Polyclonal antibody
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Uniprot No.：
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基因名：HMG20B
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宿主：Rabbit
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反應種屬：Human
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免疫原：Synthesized peptide derived from N-terminal of Human HMG20B.
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免疫原種屬：Homo sapiens (Human)
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克隆類型：Polyclonal
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純化方式：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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濃度：It differs from different batches. Please contact us to confirm it.
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產品提供形式：Liquid
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應用范圍：ELISA,WB
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推薦稀釋比：
Application Recommended Dilution WB 1:500-1:3000 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
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靶點詳情
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功能：Required for correct progression through G2 phase of the cell cycle and entry into mitosis. Required for RCOR1/CoREST mediated repression of neuronal specific gene promoters.
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基因功能參考文獻：
- Our data reveal a novel role for MID1 and for atypical ubiquitination in balancing BRAF35 presence, and likely its activity, within nuclear and cytoplasmic compartments PMID: 28760657
- Fresh insight into the mechanism by which the HMG20b-BRCA2 complex controls mitotic cell division, and implicate heterozygous HMG20b mutations affecting cytokinesis regulation in the genesis of human cancers. PMID: 25486196
- HMG20B/BRAF35 forms heterodimers with HMG20A/iBRAF. Heterodimerization impairs HMG20B/BRAF35 sumoylation and interaction with the LSD1-CoREST complex. PMID: 22570500
- a novel function for HMG20b in cytokinesis is regulated by its interaction with the BRC repeats of BRCA2 PMID: 21399666
- beta-dystrobrevin interacts with the HMG20 proteins iBRAF and BRAF35 PMID: 20530487
- molecular cloning, nucleotide and amino acid sequencing PMID: 11997092
- complex containing histone deacetylase complex containing histone deacetylase mediates repression of neuronal-specific genes. PMID: 12032298
- molecular Cloning of BRAF25, an alternatively spliced protein of BRAF35 PMID: 12083779
- Results demonstrating association of BRAF35 with KIF4 through the interaction of their respective alpha-helical coiled-coil domains is unique so far in mammals. PMID: 12809554
- we have examined Sox gene expression in 60 human primary gliomas. Transcripts from each of the six group E and group D genes were expressed in gliomas of various types and malignancy grades PMID: 17961134
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亞細胞定位：Nucleus. Chromosome. Note=Localized to condensed chromosomes in mitosis in conjunction with BRCA2.
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組織特異性：Ubiquitously expressed in adult tissues.
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數據庫鏈接：
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