HIGD1A Antibody

說明書

產品詳情

Uniprot No.：

Q9Y241
基因名：

HIGD1A
別名：

Hig1 antibody; HIG1 domain family member 1A antibody; HIG1 domain family; member 1A antibody; HIG1 hypoxia inducible domain family; member 1A antibody; HIG1A_HUMAN antibody; HIGD1A antibody; HIMP1 antibody; Hypoxia-inducible gene 1 protein antibody
宿主：

Rabbit
反應種屬：

Human,Mouse,Rat
免疫原：

Human HIGD1A
免疫原種屬：

Homo sapiens (Human)
抗體亞型：

IgG
純化方式：

Antigen Affinity purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
產品提供形式：

Liquid
應用范圍：

ELISA,WB,IF
Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
Immunofluorescence (IF) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Proposed subunit of cytochrome c oxidase (COX, complex IV), which is the terminal component of the mitochondrial respiratory chain that catalyzes the reduction of oxygen to water. May play a role in the assembly of respiratory supercomplexes.
基因功能參考文獻：
1. Nuclear localization of the mitochondrial factor HIGD1A during metabolic stress. PMID: 23646141
2. Data indicate that hypoxia-induced gene domain protein-1a (Higd-1a) inhibits Optic atrophy 1 (Opa1) cleavage and is required for mitochondrial fusion by virtue of its interaction with Opa1. PMID: 23878241
3. depletion of HIG1 increased gamma-secretase activation and enhanced hypoxia-induced mitochondrial dysfunction PMID: 22355194
亞細胞定位：

Mitochondrion membrane; Multi-pass membrane protein. Mitochondrion inner membrane.
數據庫鏈接：

HGNC: 29527

KEGG: hsa:25994

STRING: 9606.ENSP00000398064

UniGene: Hs.593134

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